PMID- 3966399
OWN - NLM
STAT- MEDLINE
DCOM- 19850129
LR  - 20190622
IS  - 0002-9149 (Print)
IS  - 0002-9149 (Linking)
VI  - 55
IP  - 1
DP  - 1985 Jan 1
TI  - Positive exercise thallium-201 test responses in patients with less than 50% 
      maximal coronary stenosis: angiographic and clinical predictors.
PG  - 54-7
AB  - The incidence and causes of abnormal thallium-201 (TI-201) myocardial perfusion 
      studies in the absence of significant coronary artery disease were examined. The 
      study group consisted of 100 consecutive patients undergoing exercise TI-201 
      testing and coronary angiography who were found to have maximal coronary artery 
      diameter narrowing of less than 50%. Maximal coronary stenosis ranged from 0 to 
      40%. The independent and relative influences of patient clinical, exercise and 
      angiographic data were assessed by logistic regression analysis. Significant 
      predictors of a positive stress TI-201 test result were: (1) percent maximal 
      coronary stenosis (p less than 0.0005), (2) propranolol use (p less than 0.01), 
      (3) interaction of propranolol use and percent maximal stenosis (p less than 
      0.005), and (4) stress-induced chest pain (p = 0.05). No other patient variable 
      had a significant influence. Positive TI-201 test results were more common in 
      patients with 21 to 40% maximal stenosis (59%) than in patients with 0 to 20% 
      maximal stenosis (27%) (p less than 0.01). Among patients with 21 to 40% 
      stenosis, a positive test response was more common when 85% of maximal predicted 
      heart rate was achieved (75%) than when it was not (40%) (p less than 0.05). Of 
      16 nonapical perfusion defects seen in patients with 21 to 40% maximal stenosis, 
      14 were in the territory that corresponded with such a coronary stenosis. 
      Patients taking propranolol were more likely to have a positive TI-201 test 
      result (45%) than patients not taking propranolol (22%) (p less than 
      0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Brown, K A
AU  - Brown KA
FAU - Osbakken, M
AU  - Osbakken M
FAU - Boucher, C A
AU  - Boucher CA
FAU - Strauss, H W
AU  - Strauss HW
FAU - Pohost, G M
AU  - Pohost GM
FAU - Okada, R D
AU  - Okada RD
LA  - eng
GR  - HL 07416/HL/NHLBI NIH HHS/United States
GR  - HL 21751/HL/NHLBI NIH HHS/United States
GR  - HL 26215/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
RN  - 0 (Radioisotopes)
RN  - 9Y8NXQ24VQ (Propranolol)
RN  - AD84R52XLF (Thallium)
SB  - IM
MH  - Coronary Angiography
MH  - Coronary Disease/*diagnostic imaging/drug therapy
MH  - Exercise Test
MH  - Female
MH  - Heart/*diagnostic imaging
MH  - Humans
MH  - Male
MH  - Propranolol/pharmacology/therapeutic use
MH  - *Radioisotopes
MH  - Radionuclide Imaging
MH  - *Thallium
EDAT- 1985/01/01 00:00
MHDA- 1985/01/01 00:01
CRDT- 1985/01/01 00:00
PHST- 1985/01/01 00:00 [pubmed]
PHST- 1985/01/01 00:01 [medline]
PHST- 1985/01/01 00:00 [entrez]
AID - 0002-9149(85)90298-X [pii]
AID - 10.1016/0002-9149(85)90298-x [doi]
PST - ppublish
SO  - Am J Cardiol. 1985 Jan 1;55(1):54-7. doi: 10.1016/0002-9149(85)90298-x.