PMID- 396765
OWN - NLM
STAT- MEDLINE
DCOM- 19800616
LR  - 20051117
IS  - 0001-6187 (Print)
IS  - 0001-6187 (Linking)
VI  - 26
IP  - 3
DP  - 1979
TI  - Shigella dysenteriae 1-like cytotoxic enterotoxins produced by Salmonella 
      strains.
PG  - 217-23
AB  - A Salmonella enteritidis strain produced a cytotoxin in addition to heat-labile 
      (LT) and heat-stable (ST) enterotoxins. Two strains of serotypes Salmonella 
      kapemba and Salmonella thompson were LT and ST negative, but exhibited a 
      cytotoxic effect. After Sephadex G-100 fractionation of the crude S. enteritidis 
      material, some high and low molecular fractions had both cytotonic and cytotoxic 
      activities. Of the two other salmonellae, only some high molecular fractions 
      contained the cytotoxic substance. Neutralization experiments revealed an 
      antigenic relationship between the cytotoxins studied and Shigella dysenteriae 1 
      enterotoxin. On the basis of cross neutralization and other data, it seems that 
      cytotoxic and LT-like characters are carried by the same molecule. In S. thompson 
      and S. kapemba the LT fails to exert a biological effect, although it is 
      antigenically related to the LT of Escherichia coli.
FAU - Ketyi, I
AU  - Ketyi I
FAU - Pacsa, S
AU  - Pacsa S
FAU - Emody, L
AU  - Emody L
FAU - Vertenyi, A
AU  - Vertenyi A
FAU - Kocsis, B
AU  - Kocsis B
FAU - Kuch, B
AU  - Kuch B
LA  - eng
PT  - Journal Article
PL  - Hungary
TA  - Acta Microbiol Acad Sci Hung
JT  - Acta microbiologica Academiae Scientiarum Hungaricae
JID - 0370333
RN  - 0 (Antigens, Bacterial)
RN  - 0 (Cytotoxins)
RN  - 0 (Enterotoxins)
SB  - IM
MH  - Animals
MH  - Antigens, Bacterial/analysis
MH  - Cell Line
MH  - Cricetinae
MH  - Cytotoxins/*biosynthesis/immunology
MH  - Enterotoxins/*biosynthesis/immunology
MH  - Escherichia coli
MH  - Humans
MH  - Neutralization Tests
MH  - Salmonella/*metabolism
MH  - Salmonella enteritidis/*metabolism
MH  - Shigella dysenteriae
EDAT- 1979/01/01 00:00
MHDA- 1979/01/01 00:01
CRDT- 1979/01/01 00:00
PHST- 1979/01/01 00:00 [pubmed]
PHST- 1979/01/01 00:01 [medline]
PHST- 1979/01/01 00:00 [entrez]
PST - ppublish
SO  - Acta Microbiol Acad Sci Hung. 1979;26(3):217-23.