PMID- 3971947
OWN - NLM
STAT- MEDLINE
DCOM- 19850409
LR  - 20190813
IS  - 0013-9580 (Print)
IS  - 0013-9580 (Linking)
VI  - 26
IP  - 1
DP  - 1985 Jan-Feb
TI  - HLA antigens and idiopathic epilepsy.
PG  - 15-8
AB  - Fifty-two mentally normal Egyptian children with idiopathic epilepsy were human 
      leukocyte antigen (HLA) typed. They were divided into two subgroups: generalized 
      tonic-clonic seizures (36 cases) and absences (16 cases). When the frequencies of 
      HLA antigens were compared statistically with those of 120 normal controls, 
      HLA-A9 was found to be significantly higher in the total epilepsy group and the 
      two subgroups. This finding, together with the low HLA-A9 gene frequency in our 
      group of normal Egyptians as compared with other ethnic populations, strongly 
      suggests an association between antigen A9 and one or more of the polygenes 
      controlling the development of idiopathic epilepsy. The relative risk indicated 
      that persons having antigen A9 are 16 times more susceptible to epilepsy than 
      persons lacking it.
FAU - Hafez, M
AU  - Hafez M
FAU - Nagaty, M
AU  - Nagaty M
FAU - Saied, E
AU  - Saied E
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Epilepsia
JT  - Epilepsia
JID - 2983306R
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Epilepsy/*genetics
MH  - Female
MH  - HLA Antigens/*analysis
MH  - Humans
MH  - Male
EDAT- 1985/01/01 00:00
MHDA- 1985/01/01 00:01
CRDT- 1985/01/01 00:00
PHST- 1985/01/01 00:00 [pubmed]
PHST- 1985/01/01 00:01 [medline]
PHST- 1985/01/01 00:00 [entrez]
AID - 10.1111/j.1528-1157.1985.tb05183.x [doi]
PST - ppublish
SO  - Epilepsia. 1985 Jan-Feb;26(1):15-8. doi: 10.1111/j.1528-1157.1985.tb05183.x.