PMID- 3984881 OWN - NLM STAT- MEDLINE DCOM- 19850507 LR - 20190622 IS - 0002-9149 (Print) IS - 0002-9149 (Linking) VI - 55 IP - 8 DP - 1985 Apr 1 TI - Prognosis with chest pain and normal thallium-201 exercise scintigrams. PG - 920-6 AB - The goal of this study was to determine the prognostic value of a normal exercise thallium-201 (TI-201) scintigram by quantitative criteria in a consecutive series of 349 patients with chest pain. Follow-up was obtained in 345 patients (99%) from 8 to 45 months (mean 34 +/- 7). Of these, 60% were men, 26% had typical angina, 21% had chest pain during exercise testing, 29% were unable to achieve 85% or more of maximal predicted heart rate, and in 9% ischemic ST depression (1.0 mm or greater) developed during exercise. At the time of exercise testing, 45% of patients were taking nitrates and 38% were receiving a beta-blocking drug. During the follow-up period, there were 5 cardiac deaths (0.51%/year), of which 2 were sudden, 6 patients had a nonfatal myocardial infarction (MI) (0.61%/year). Two of the 5 patients who died and 1 who had MI had angiographically normal coronary arteries. The event rate was significantly higher (p less than 0.01) in patients referred for early catheterization (5 of 53; 9%) compared with the rate for those not undergoing early angiography (6 of 298; 2%). However, the event rate was similar in those who underwent catheterization with angiographically normal coronary arteries and in those who had significant coronary artery disease.(ABSTRACT TRUNCATED AT 250 WORDS) FAU - Pamelia, F X AU - Pamelia FX FAU - Gibson, R S AU - Gibson RS FAU - Watson, D D AU - Watson DD FAU - Craddock, G B AU - Craddock GB FAU - Sirowatka, J AU - Sirowatka J FAU - Beller, G A AU - Beller GA LA - eng GR - 1 R0 1 HL26205/HL/NHLBI NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Am J Cardiol JT - The American journal of cardiology JID - 0207277 RN - 0 (Radioisotopes) RN - AD84R52XLF (Thallium) SB - IM MH - Adult MH - Coronary Angiography MH - Coronary Disease/complications/diagnosis/*diagnostic imaging MH - Exercise Test MH - Female MH - Follow-Up Studies MH - Heart/diagnostic imaging MH - Humans MH - Male MH - Middle Aged MH - Pain/*etiology MH - Prognosis MH - *Radioisotopes MH - Radionuclide Imaging MH - *Thallium MH - *Thorax EDAT- 1985/04/01 00:00 MHDA- 1985/04/01 00:01 CRDT- 1985/04/01 00:00 PHST- 1985/04/01 00:00 [pubmed] PHST- 1985/04/01 00:01 [medline] PHST- 1985/04/01 00:00 [entrez] AID - 0002-9149(85)90718-0 [pii] AID - 10.1016/0002-9149(85)90718-0 [doi] PST - ppublish SO - Am J Cardiol. 1985 Apr 1;55(8):920-6. doi: 10.1016/0002-9149(85)90718-0.