PMID- 3987281
OWN - NLM
STAT- MEDLINE
DCOM- 19850607
LR  - 20190824
IS  - 0010-7824 (Print)
IS  - 0010-7824 (Linking)
VI  - 31
IP  - 2
DP  - 1985 Feb
TI  - In vitro amplification of toxic shock syndrome toxin-1 by intravaginal devices.
PG  - 185-94
AB  - Super-absorbent tampons and an exotoxin of Staphylococcus aureus have been 
      associated with the recent emergence of toxic shock syndrome (TSS). In the 
      majority of cases, when a TSS strain of S. aureus was cultivated in the presence 
      of various tampons and a contraceptive sponge, increased amounts of toxic shock 
      syndrome toxin-1 (TSST-1) were observed to be produced into the blood medium by 
      the bacterium. The amplification of toxin by these products adds support to the 
      epidemiologic data in establishing the causal link between tampons and TSS.
FAU - Tierno, P M Jr
AU  - Tierno PM Jr
FAU - Hanna, B A
AU  - Hanna BA
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Contraception
JT  - Contraception
JID - 0234361
RN  - 0 (Bacterial Toxins)
RN  - 0 (Enterotoxins)
RN  - 0 (Superantigens)
RN  - 0 (enterotoxin F, Staphylococcal)
SB  - IM
MH  - *Bacterial Toxins
MH  - Contraceptive Devices, Female/*adverse effects
MH  - Enterotoxins/*metabolism
MH  - Female
MH  - Humans
MH  - Shock, Septic/*microbiology
MH  - Staphylococcus aureus/pathogenicity
MH  - *Superantigens
MH  - Tampons, Surgical/*adverse effects
MH  - Virulence
EDAT- 1985/02/01 00:00
MHDA- 2001/03/28 10:01
CRDT- 1985/02/01 00:00
PHST- 1985/02/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1985/02/01 00:00 [entrez]
AID - 0010-7824(85)90033-2 [pii]
AID - 10.1016/0010-7824(85)90033-2 [doi]
PST - ppublish
SO  - Contraception. 1985 Feb;31(2):185-94. doi: 10.1016/0010-7824(85)90033-2.