PMID- 3997792
OWN - NLM
STAT- MEDLINE
DCOM- 19850708
LR  - 20190511
IS  - 0021-924X (Print)
IS  - 0021-924X (Linking)
VI  - 97
IP  - 1
DP  - 1985 Jan
TI  - Bile acid profiles in analbuminemia rats.
PG  - 199-203
AB  - Bile acid profiles in serum, urine and bile of Nagase analbuminemia rats (NAR) 
      and Sprague-Dawley rats (SDR) were examined. Serum bile acid levels in NAR (2.02 
      + 0.51 micrograms/ml, n = 15, M +/- S.E.) were markedly decreased as compared 
      with those in SDR (20.86 +/- 3.72 micrograms/ml, n = 10). The unbound fraction of 
      acids in serum examined by equilibrium dialysis was about ten times higher in NAR 
      than in SDR. In the profiles of urinary and biliary bile acids in NAR and SDR, as 
      big differences as seen for serum bile acids were not observed. Low bile acid 
      levels in serum of NAR may reflect low bile acid binding capacity of NAR serum 
      because the absence of albumin was thought to be one of the major causes of low 
      bile acid levels in serum of NAR.
FAU - Takikawa, H
AU  - Takikawa H
FAU - Seyama, Y
AU  - Seyama Y
FAU - Sugiyama, Y
AU  - Sugiyama Y
FAU - Nagase, S
AU  - Nagase S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Biochem
JT  - Journal of biochemistry
JID - 0376600
RN  - 0 (Bile Acids and Salts)
RN  - 0 (Cholic Acids)
RN  - 0 (Serum Albumin)
RN  - 5E090O0G3Z (Taurocholic Acid)
RN  - 5QU0I8393U (Lithocholic Acid)
RN  - G1JO7801AE (Cholic Acid)
SB  - IM
MH  - Aging
MH  - Animals
MH  - Bile/metabolism
MH  - Bile Acids and Salts/blood/*metabolism/urine
MH  - Cholic Acid
MH  - Cholic Acids/metabolism
MH  - Gas Chromatography-Mass Spectrometry
MH  - Lithocholic Acid/metabolism
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Rats, Mutant Strains
MH  - Serum Albumin/*deficiency
MH  - Taurocholic Acid/metabolism
EDAT- 1985/01/01 00:00
MHDA- 1985/01/01 00:01
CRDT- 1985/01/01 00:00
PHST- 1985/01/01 00:00 [pubmed]
PHST- 1985/01/01 00:01 [medline]
PHST- 1985/01/01 00:00 [entrez]
AID - 10.1093/oxfordjournals.jbchem.a135045 [doi]
PST - ppublish
SO  - J Biochem. 1985 Jan;97(1):199-203. doi: 10.1093/oxfordjournals.jbchem.a135045.