PMID- 4031992
OWN - NLM
STAT- MEDLINE
DCOM- 19851007
LR  - 20171213
IS  - 0022-3077 (Print)
IS  - 0022-3077 (Linking)
VI  - 54
IP  - 2
DP  - 1985 Aug
TI  - Spontaneous and driven responses of semicircular canal primary afferents in the 
      unanesthetized pigeon.
PG  - 335-47
AB  - Spontaneous activity from 120 vestibular semicircular canal (SC) primary 
      afferents and driven responses from 20 SC primary afferents to 2.3-decade 
      bandwidth (0.029-6.152 Hz) sum of sinusoidal angular rotations were characterized 
      in 10 unanesthetized pigeons. The results were compared with those previously 
      gathered from barbiturate anesthetized pigeons. The average spontaneous mean 
      firing rate (MFR) of SC primary afferents in unanesthetized pigeons was found to 
      be 168 impulses per second (I/s), n = 120, and is approximately 80% higher than 
      that for SC primary afferents in anesthetized pigeons [93 I/s, n = 149 (Ref. 9) 
      and 92 I/s, n = 124 (Ref. 22)]. The spontaneous discharge of SC primary afferents 
      from unanesthetized pigeons was classified according to the coefficient of 
      variation (CV) of 512-1,024 interspike intervals (ISIs) into regular (CV less 
      than 0.1), intermediate (0.1 less than or equal to CV less 0.4), and irregular 
      (0.4 less than or equal to CV) categories. The percentages of SC primary 
      afferents falling within each CV category were similar for unanesthetized and 
      anesthetized pigeons (22). The relation between the spontaneous mean ISI and its 
      standard deviation (SD) for SC primary afferents in the unanesthetized pigeon is 
      best described by a power function model, which provides a significantly better 
      fit than does a linear model. The parameters of this power function model are 
      similar for SC primary afferents in unanesthetized and anesthetized pigeons (10). 
      The spontaneous ISIs of individual SC primary afferents in the unanesthetized 
      pigeon were found to be distributed either normally, log-normally, or according 
      to the first passage time of the Wiener-Levy (WL) process. The gain of anterior 
      SC primary afferents at 0.25 Hz is similar for anesthetized (2.93 I X s-1 X deg-1 
      X s-1, n = 14) (11) and for unanesthetized (3.01 I X s-1 X deg-1 X s-1, n = 14) 
      pigeons. Bode plots constructed from the responses to sum sinusoidal angular 
      accelerations reveal that SC primary afferents in unanesthetized pigeons display 
      a phase lead and gain enhancement at frequencies between 0.6 and 6 Hz.(ABSTRACT 
      TRUNCATED AT 400 WORDS)
FAU - Anastasio, T J
AU  - Anastasio TJ
FAU - Correia, M J
AU  - Correia MJ
FAU - Perachio, A A
AU  - Perachio AA
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - United States
TA  - J Neurophysiol
JT  - Journal of neurophysiology
JID - 0375404
RN  - 0 (Barbiturates)
SB  - IM
MH  - Action Potentials
MH  - Anesthesia, General
MH  - Animals
MH  - Barbiturates/pharmacology
MH  - Columbidae/*physiology
MH  - Macaca mulatta
MH  - Neurons, Afferent/physiology
MH  - Saimiri
MH  - Semicircular Canals/*innervation
MH  - Vestibular Nerve/drug effects/*physiology
OID - NASA: 85292011
EDAT- 1985/08/01 00:00
MHDA- 1985/08/01 00:01
CRDT- 1985/08/01 00:00
PHST- 1985/08/01 00:00 [pubmed]
PHST- 1985/08/01 00:01 [medline]
PHST- 1985/08/01 00:00 [entrez]
AID - 10.1152/jn.1985.54.2.335 [doi]
PST - ppublish
SO  - J Neurophysiol. 1985 Aug;54(2):335-47. doi: 10.1152/jn.1985.54.2.335.