PMID- 4033106 OWN - NLM STAT- MEDLINE DCOM- 19851018 LR - 20190817 IS - 0022-4804 (Print) IS - 0022-4804 (Linking) VI - 39 IP - 3 DP - 1985 Sep TI - Determination of heat gain in the inferior vena cava during thermodilution measurements. PG - 224-9 AB - The measurement of blood flow in the inferior vena cava (IVC) by thermodilution may be useful in the determination of hepatic venous blood flow (HVBF), but is subject to major errors. The most serious error is gain of heat from the abdominal viscera by the cool thermodiluent bolus as it moves up the IVC. The determination or elimination of this heat gain is necessary for accurate IVC blood flow measurement. By comparison of the area under the curve (AUC) for cardiac output following femoral vein injection of the thermodiluent bolus to the AUC following right ventricular injection of the thermodiluent, it is possible to quantitatively determine the unidirectional heat gain by the bolus at it moves up the IVC. The heat gain varied from 0 to 40% of the thermodiluent injected. The factors that aggravated the heat gain were a low cardiac output (below 4000 ml/mn), a large thermodiluent calorie load (over -40 calories), and possibly a slow transit time. The error due to heat gain may be effectively eliminated by keeping the size of the thermodiluent bolus below 40 negative calories. FAU - Bryant, G H AU - Bryant GH FAU - Cucinell, S A AU - Cucinell SA FAU - Barcia, P J AU - Barcia PJ LA - eng PT - Journal Article PL - United States TA - J Surg Res JT - The Journal of surgical research JID - 0376340 SB - IM MH - Animals MH - Body Temperature Regulation MH - Cardiac Output MH - Hepatic Veins/*physiology MH - Hot Temperature MH - Regional Blood Flow MH - Swine MH - Vena Cava, Inferior/*physiology EDAT- 1985/09/01 00:00 MHDA- 1985/09/01 00:01 CRDT- 1985/09/01 00:00 PHST- 1985/09/01 00:00 [pubmed] PHST- 1985/09/01 00:01 [medline] PHST- 1985/09/01 00:00 [entrez] AID - 0022-4804(85)90146-5 [pii] AID - 10.1016/0022-4804(85)90146-5 [doi] PST - ppublish SO - J Surg Res. 1985 Sep;39(3):224-9. doi: 10.1016/0022-4804(85)90146-5.