PMID- 4038944 OWN - NLM STAT- MEDLINE DCOM- 19850520 LR - 20190816 IS - 0014-4835 (Print) IS - 0014-4835 (Linking) VI - 40 IP - 2 DP - 1985 Feb TI - Immunoglobulin E in aqueous humour. PG - 321-5 AB - The level of immunoglobulin E (IgE) was determined in the aqueous humour (AH) and serum by particle counting immunoassay (limit of sensitivity: 0.2 IU ml-1). This level in the AH was below 0.75 IU ml-1 in case of senile cataract (n = 22) and ranged from this assumed normal value to 550 IU ml-1 in case of uveitis (n = 37), Fuchs' cyclitis (n = 11), intraocular tumour (n = 7) and perforating ocular injury (n = 6). To know whether the IgE increase was related to a possible local production the AH/serum concentration ratio for IgE was calculated and divided by that for albumin. Values higher than 0.60 were considered as suggestive of a local synthesis and were observed in 31 of the 37 samples examined. FAU - Dernouchamps, J P AU - Dernouchamps JP FAU - Magnusson, C G AU - Magnusson CG FAU - Michiels, J AU - Michiels J FAU - Masson, P L AU - Masson PL LA - eng PT - Journal Article PL - England TA - Exp Eye Res JT - Experimental eye research JID - 0370707 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Aqueous Humor/*immunology MH - Cataract/immunology MH - Eye Injuries/immunology MH - Eye Neoplasms/immunology MH - Humans MH - Immunoglobulin E/*analysis/biosynthesis MH - Uveitis/immunology MH - Uveitis, Anterior/immunology EDAT- 1985/02/01 00:00 MHDA- 1985/02/01 00:01 CRDT- 1985/02/01 00:00 PHST- 1985/02/01 00:00 [pubmed] PHST- 1985/02/01 00:01 [medline] PHST- 1985/02/01 00:00 [entrez] AID - 0014-4835(85)90016-8 [pii] AID - 10.1016/0014-4835(85)90016-8 [doi] PST - ppublish SO - Exp Eye Res. 1985 Feb;40(2):321-5. doi: 10.1016/0014-4835(85)90016-8.