PMID- 4051029
OWN - NLM
STAT- MEDLINE
DCOM- 19851112
LR  - 20171213
IS  - 0002-9513 (Print)
IS  - 0002-9513 (Linking)
VI  - 249
IP  - 4 Pt 2
DP  - 1985 Oct
TI  - Nutrient control of cardiac rate in infant rats: role of arterial baroreceptors.
PG  - R443-8
AB  - A surgical procedure is described for the deafferentation of carotid sinus (CS) 
      and aortic depressor (AD) baroreceptors in 2-wk suckling rats. Baroreflex testing 
      in unanesthetized pups showed that cardiac rate responses to acute elevations of 
      blood pressure were reduced to less than 9% of controls after combined 
      denervation (CSAD), 28% after AD and 47% after CS denervation at 4 h. After 24 h 
      of nutrient deprivation, resting cardiac rates of sham operated controls fell a 
      mean of -148 beat/min, significantly more than CS, AD, or CSAD groups (P less 
      than 0.01). Baroreflex test responses in individuals correlated significantly 
      with their later responses to nutrient deprivation (r = 0.67, P less than 0.01). 
      There were no significant differences in base-line cardiac rate, systolic blood 
      pressure, or cardiac rate during 24 h intragastric milk infusion between 
      deafferented and control pups. These experiments suggest that arterial 
      baroreceptors are important in the cardiovascular adjustments after nutrient 
      deprivation in suckling rats.
FAU - Hofer, M A
AU  - Hofer MA
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Physiol
JT  - The American journal of physiology
JID - 0370511
SB  - IM
MH  - Afferent Pathways/physiology
MH  - Animal Population Groups/*physiology
MH  - Animals
MH  - Animals, Suckling/*physiology
MH  - Blood Pressure
MH  - Carotid Sinus/physiology
MH  - Denervation
MH  - Electrodes, Implanted
MH  - Food Deprivation/*physiology
MH  - *Heart Rate
MH  - Pressoreceptors/*physiology
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Reflex/physiology
MH  - Time Factors
EDAT- 1985/10/01 00:00
MHDA- 1985/10/01 00:01
CRDT- 1985/10/01 00:00
PHST- 1985/10/01 00:00 [pubmed]
PHST- 1985/10/01 00:01 [medline]
PHST- 1985/10/01 00:00 [entrez]
AID - 10.1152/ajpregu.1985.249.4.R443 [doi]
PST - ppublish
SO  - Am J Physiol. 1985 Oct;249(4 Pt 2):R443-8. doi: 10.1152/ajpregu.1985.249.4.R443.