PMID- 4059891
OWN - NLM
STAT- MEDLINE
DCOM- 19851220
LR  - 20190908
IS  - 0355-3140 (Print)
IS  - 0355-3140 (Linking)
VI  - 11
IP  - 4
DP  - 1985 Aug
TI  - Exposure to microorganisms, febrile and airway-obstructive symptoms, immune 
      status and lung function of Swedish farmers.
PG  - 287-93
AB  - A questionnaire was sent to 512 farmers, members of a local farmer's health 
      association. Eighty were interviewed, and their serum precipitins and total serum 
      immunoglobulin E (IgE) values were determined. Forty-five underwent extensive 
      pulmonary function tests. On the basis of the clinical evaluation it was 
      estimated that 19% of the farmers had experienced febrile reactions (fever and/or 
      shivering) following exposure to organic dust, 50% of the 19% having been exposed 
      within the last 2.5 years. Common causes were moldy grain, hay, and woodchips. 
      The pulmonary function, gas exchange, and chest radiographs of those who had 
      previously had febrile reactions were normal. Only 13% showed positive precipitin 
      reactions in Ouchterlony double-diffusion tests. With more sensitive tests, 
      positive precipitins were found in 59%, but they were negatively correlated with 
      febrile episodes. Air samples collected during work with hay and grain on 21 
      farms contained between 10(7) to 2 X 10(9) microorganisms/m3. The highest values 
      were associated with symptoms of alveolitis. Eleven percent of the farmers 
      reported obstructive chest symptoms following exposure to organic dust. This 
      group showed decreased pulmonary function and elevated serum IgE levels and 
      included a high proportion of smokers and exsmokers. No correlation was found 
      between febrile and obstructive reactions.
FAU - Malmberg, P
AU  - Malmberg P
FAU - Rask-Andersen, A
AU  - Rask-Andersen A
FAU - Palmgren, U
AU  - Palmgren U
FAU - Hoglund, S
AU  - Hoglund S
FAU - Kolmodin-Hedman, B
AU  - Kolmodin-Hedman B
FAU - Stalenheim, G
AU  - Stalenheim G
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Finland
TA  - Scand J Work Environ Health
JT  - Scandinavian journal of work, environment & health
JID - 7511540
RN  - 0 (Allergens)
RN  - 0 (Dust)
RN  - 0 (Precipitins)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Agricultural Workers' Diseases/*epidemiology
MH  - Air Microbiology
MH  - Allergens
MH  - Alveolitis, Extrinsic Allergic/epidemiology
MH  - Dust
MH  - Farmer's Lung/epidemiology
MH  - Female
MH  - Fever/epidemiology
MH  - Humans
MH  - Immunoglobulin E/*analysis
MH  - Lung/*physiopathology
MH  - Lung Diseases, Obstructive/*epidemiology
MH  - Male
MH  - Middle Aged
MH  - Precipitins/*analysis
MH  - Respiratory Function Tests
MH  - Sweden
EDAT- 1985/08/01 00:00
MHDA- 1985/08/01 00:01
CRDT- 1985/08/01 00:00
PHST- 1985/08/01 00:00 [pubmed]
PHST- 1985/08/01 00:01 [medline]
PHST- 1985/08/01 00:00 [entrez]
AID - 2220 [pii]
AID - 10.5271/sjweh.2220 [doi]
PST - ppublish
SO  - Scand J Work Environ Health. 1985 Aug;11(4):287-93. doi: 10.5271/sjweh.2220.