PMID- 4083783
OWN - NLM
STAT- MEDLINE
DCOM- 19860220
LR  - 20131121
IS  - 0355-9521 (Print)
IS  - 0355-9521 (Linking)
VI  - 74
IP  - 5
DP  - 1985
TI  - Acute renal failure related to open-heart surgery.
PG  - 203-9
AB  - Open-heart surgery was performed on 1686 adult patients between 1980 and 1984. 
      The patients were operated on using cardiopulmonary bypass procedures (CPB). 
      Fifteen patients developed acute renal failure (ARF) after CPB, i.e. the 
      incidence of ARF was 0.9%. All these patients were treated by peritoneal dialysis 
      or haemodialysis. Pre-operative possible risk factors in the ARF group were 
      compared to those in a control group of 30 patients (15 consecutive coronary 
      artery bypass grafting and 15 consecutive valve repair procedures) experiencing 
      no complications. Age, New York Heart Association (NYHA) classification, ejection 
      fraction, cardiac volume and left ventricular end-diastolic pressure were not 
      risk factors for the development of renal failure. The incidence of 
      thrombocytopenia after CPB was statistically significantly different between the 
      control and ARF groups. The mortality from ARF was 66.6%. The causes of death 
      were peri-operative myocardial infarction, infection and gastrointestinal 
      bleeding. CPB time, perioperative events and postoperative infection were the 
      main factors contributing to ARF. Renal failure was twice as common in valve 
      procedures as in coronary artery revascularization procedures. Impairment of 
      renal function proved reversible only in those patients who survived. After 
      restoration of renal function the prognosis was good.
FAU - Heikkinen, L
AU  - Heikkinen L
FAU - Harjula, A
AU  - Harjula A
FAU - Merikallio, E
AU  - Merikallio E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Finland
TA  - Ann Chir Gynaecol
JT  - Annales chirurgiae et gynaecologiae
JID - 7609767
RN  - AYI8EX34EU (Creatinine)
RN  - RWP5GA015D (Potassium)
SB  - IM
MH  - Acute Kidney Injury/*etiology/mortality/therapy
MH  - Adult
MH  - Aged
MH  - Cardiac Output
MH  - Cardiopulmonary Bypass/*adverse effects/mortality
MH  - Creatinine/blood
MH  - Female
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Peritoneal Dialysis
MH  - Platelet Count
MH  - Potassium/blood
MH  - Renal Dialysis
MH  - Reoperation
MH  - Risk
MH  - Urine/metabolism
EDAT- 1985/01/01 00:00
MHDA- 1985/01/01 00:01
CRDT- 1985/01/01 00:00
PHST- 1985/01/01 00:00 [pubmed]
PHST- 1985/01/01 00:01 [medline]
PHST- 1985/01/01 00:00 [entrez]
PST - ppublish
SO  - Ann Chir Gynaecol. 1985;74(5):203-9.