PMID- 4373151 OWN - NLM STAT- MEDLINE DCOM- 19750310 LR - 20181113 IS - 0008-4050 (Print) IS - 0008-4050 (Linking) VI - 38 IP - 4 DP - 1974 Oct TI - Minimal inhibitory concentrations of twenty antimicrobial agents to animal pathogens. PG - 437-42 AB - Minimal inhibitory concentration (M.I.C.) values as determined by an agar-plate-dilution method for 60 bacterial isolates, consisting of Salmonella typhimurium, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus of animal origin against 20 antimicrobial drugs are presented. Of all the drugs, gentamicin had the best in vitro antibacterial activity in terms of M.I.C. when considering all the species of organisms together, while spectinomycin had the least activity.An inoculum replicator was a convenient tool in carrying out the agar-plate-dilution method.A comparison of the M.I.C. values of 42 isolates of S. typhimurium with the results obtained by low level method and the Bauer-Kir-by method showed that with few exceptions, there is a general agreement. FAU - Hariharan, H AU - Hariharan H FAU - Barnum, D A AU - Barnum DA LA - eng PT - Journal Article PL - Canada TA - Can J Comp Med JT - Canadian journal of comparative medicine : Revue canadienne de medecine comparee JID - 0151747 RN - 0 (Anti-Bacterial Agents) RN - 0 (Gentamicins) RN - 0 (Leucomycins) RN - 0 (Penicillins) RN - 0 (Polymyxins) RN - 11006-76-1 (Virginiamycin) RN - 17EC19951N (Novobiocin) RN - 3B91HWA56M (Nalidixic Acid) RN - 4BOC774388 (Framycetin) RN - 59-01-8 (Kanamycin) RN - 63937KV33D (Erythromycin) RN - 66974FR9Q1 (Chloramphenicol) RN - 7C782967RD (Ampicillin) RN - 93AKI1U6QF (Spectinomycin) RN - BOD072YW0F (Lincomycin) RN - LVZ1VC61HB (Cephaloridine) RN - O6X5QGC2VB (Cloxacillin) RN - P8ZQ646136 (Oleandomycin) RN - Q91FH1328A (Methicillin) SB - IM MH - Ampicillin/pharmacology MH - Anti-Bacterial Agents/*pharmacology MH - Bacteria/*drug effects MH - Cephaloridine/pharmacology MH - Chloramphenicol/pharmacology MH - Cloxacillin/pharmacology MH - Erythromycin/pharmacology MH - Escherichia coli/drug effects MH - Framycetin/pharmacology MH - Gentamicins/pharmacology MH - Kanamycin/pharmacology MH - Leucomycins/pharmacology MH - Lincomycin/pharmacology MH - Methicillin/pharmacology MH - Microbial Sensitivity Tests MH - Nalidixic Acid/pharmacology MH - Novobiocin/pharmacology MH - Oleandomycin/pharmacology MH - Penicillin Resistance MH - Penicillins/pharmacology MH - Polymyxins/pharmacology MH - Pseudomonas aeruginosa/drug effects MH - Salmonella typhimurium/drug effects MH - Spectinomycin/pharmacology MH - Staphylococcus/drug effects MH - Virginiamycin/pharmacology PMC - PMC1319848 EDAT- 1974/10/01 00:00 MHDA- 1974/10/01 00:01 PMCR- 1974/10/01 CRDT- 1974/10/01 00:00 PHST- 1974/10/01 00:00 [pubmed] PHST- 1974/10/01 00:01 [medline] PHST- 1974/10/01 00:00 [entrez] PHST- 1974/10/01 00:00 [pmc-release] PST - ppublish SO - Can J Comp Med. 1974 Oct;38(4):437-42.