PMID- 453999
OWN - NLM
STAT- MEDLINE
DCOM- 19790816
LR  - 20220408
IS  - 0003-4975 (Print)
IS  - 0003-4975 (Linking)
VI  - 27
IP  - 4
DP  - 1979 Apr
TI  - Mitral valve replacement: a nine-year follow-up of risks and survivals.
PG  - 312-9
AB  - Experience with mitral valve replacement over a nine-year period is reviewed. 
      Hospital mortality was 8.9%, with an additional late mortality of 18.5% during a 
      mean follow-up period of 4.34 years. Study of the factors influencing the results 
      of valve replacement revealed a direct correlation between long-term survival and 
      New York Heart Association (NYHA) Functional Class, as judged preoperatively, as 
      well as left ventricular end-diastolic pressure, cardiac index, type of valve 
      lesion, and presence of associated coronary artery disease. Hospital mortality 
      was 32% (p less than 0.01) for those patients in NYHA Functional Class IV before 
      operation, compared with 3% for Class III patients. Untreated concomitant 
      coronary artery disease was associated with a significantly higher perioperative 
      mortality of 28% (p = 0.002) compared with an 8% mortality in patients with 
      coronary artery disease treated by vein bypass at the time of mitral valve 
      replacement. Patients with normal coronary arteries documented angiographically 
      before operation had a 1% hospital mortality. Seventy-two percent of all patients 
      are still alive at a maximum follow-up of nine years. Eighty-three percent of 
      those survivors who were in Functional Class III or IV before operation are now 
      considered to be in Class I or II. We conclude that patients should undergo 
      mitral valve replacement before the development of the advanced functional stage 
      of valve disease. In addition, coronary arteriograms should be performed on all 
      patients who are more than 40 years old at the time of cardiac catheterization, 
      and revascularization considered at the time of mitral valve replacement for 
      those patients with significant coronary disease.
FAU - Chaffin, J S
AU  - Chaffin JS
FAU - Daggett, W M
AU  - Daggett WM
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Ann Thorac Surg
JT  - The Annals of thoracic surgery
JID - 15030100R
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Coronary Disease/complications/mortality
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Valve Prosthesis/*mortality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Insufficiency/complications/mortality/*surgery
MH  - Mitral Valve Stenosis/complications/mortality/*surgery
MH  - Risk
MH  - Time Factors
EDAT- 1979/04/01 00:00
MHDA- 1979/04/01 00:01
CRDT- 1979/04/01 00:00
PHST- 1979/04/01 00:00 [pubmed]
PHST- 1979/04/01 00:01 [medline]
PHST- 1979/04/01 00:00 [entrez]
AID - S0003-4975(10)63305-X [pii]
AID - 10.1016/s0003-4975(10)63305-x [doi]
PST - ppublish
SO  - Ann Thorac Surg. 1979 Apr;27(4):312-9. doi: 10.1016/s0003-4975(10)63305-x.