PMID- 4553001
OWN - NLM
STAT- MEDLINE
DCOM- 19720620
LR  - 20210526
IS  - 0021-9193 (Print)
IS  - 1098-5530 (Electronic)
IS  - 0021-9193 (Linking)
VI  - 110
IP  - 1
DP  - 1972 Apr
TI  - Effects of acridine orange on the growth of Escherichia coli.
PG  - 439-41
AB  - Exposure of Escherichia coli to critical acridine orange (AO) concentrations did 
      not result in loss of viability. However, the deoxyribonucleic acid (DNA) of 
      cells exposed to such agents was rapidly degraded and repolymerized. On the other 
      hand, a bacterium deficient in DNA repair (pol A(1) (-), lacking DNA polymerase) 
      was sensitive to the action of AO. The DNA of such cells was also degraded but it 
      was not repaired.
FAU - Southwick, F S
AU  - Southwick FS
FAU - Carr, H S
AU  - Carr HS
FAU - Carden, G A 3rd
AU  - Carden GA 3rd
FAU - D'Alisa, R M
AU  - D'Alisa RM
FAU - Rosenkranz, H S
AU  - Rosenkranz HS
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Bacteriol
JT  - Journal of bacteriology
JID - 2985120R
RN  - 0 (Acridines)
RN  - 0 (Carbon Isotopes)
RN  - 0 (DNA, Bacterial)
RN  - EC 2.7.7.- (DNA Nucleotidyltransferases)
RN  - VC2W18DGKR (Thymidine)
SB  - IM
MH  - Acridines/*pharmacology
MH  - Carbon Isotopes
MH  - Centrifugation, Density Gradient
MH  - DNA Nucleotidyltransferases
MH  - DNA Repair
MH  - DNA, Bacterial/isolation & purification/metabolism
MH  - Escherichia coli/*drug effects/growth & development/metabolism
MH  - Genetics, Microbial
MH  - Kinetics
MH  - Mutation
MH  - Thymidine/metabolism
PMC - PMC247425
EDAT- 1972/04/01 00:00
MHDA- 1972/04/01 00:01
PMCR- 1972/04/01
CRDT- 1972/04/01 00:00
PHST- 1972/04/01 00:00 [pubmed]
PHST- 1972/04/01 00:01 [medline]
PHST- 1972/04/01 00:00 [entrez]
PHST- 1972/04/01 00:00 [pmc-release]
AID - 10.1128/jb.110.1.439-441.1972 [doi]
PST - ppublish
SO  - J Bacteriol. 1972 Apr;110(1):439-41. doi: 10.1128/jb.110.1.439-441.1972.