PMID- 4643397 OWN - NLM STAT- MEDLINE DCOM- 19730228 LR - 20190501 IS - 0007-1447 (Print) IS - 0007-1447 (Linking) VI - 4 IP - 5840 DP - 1972 Dec 9 TI - Anaesthesia in sickle-cell states: a plea for simplicity. PG - 596-8 AB - 505 patients with various haemoglobinopathies were given a general anaesthetic between January 1970 and February 1972. One patient with haemoglobin SC disease and one patient with sickle-cell trait (HbAS) died postoperatively. Four other patients who were sickling positive, but whose genotypes were unknown, died, one from sickle-cell crisis precipitated by haemorrhage.A simple anaesthetic technique together with good postoperative care can provide safe general anaesthesia for patients with sickle-cell states. A plea is made for simplicity in the anaesthetic management of these patients. FAU - Oduro, K A AU - Oduro KA FAU - Searle, J F AU - Searle JF LA - eng PT - Journal Article PL - England TA - Br Med J JT - British medical journal JID - 0372673 SB - IM MH - Adult MH - Aged MH - *Anemia, Sickle Cell MH - Anesthesia/*adverse effects MH - Female MH - Genotype MH - Hemoglobin C Disease MH - Hemoglobinopathies MH - Hemorrhage/etiology MH - Humans MH - Male MH - Methods MH - Middle Aged MH - Postoperative Care MH - Postoperative Complications/prevention & control MH - Thalassemia PMC - PMC1786847 EDAT- 1972/12/09 00:00 MHDA- 1972/12/09 00:01 PMCR- 1972/12/09 CRDT- 1972/12/09 00:00 PHST- 1972/12/09 00:00 [pubmed] PHST- 1972/12/09 00:01 [medline] PHST- 1972/12/09 00:00 [entrez] PHST- 1972/12/09 00:00 [pmc-release] AID - 10.1136/bmj.4.5840.596 [doi] PST - ppublish SO - Br Med J. 1972 Dec 9;4(5840):596-8. doi: 10.1136/bmj.4.5840.596.