PMID- 498586 OWN - NLM STAT- MEDLINE DCOM- 19800124 LR - 20181113 IS - 0009-9104 (Print) IS - 1365-2249 (Electronic) IS - 0009-9104 (Linking) VI - 37 IP - 2 DP - 1979 Aug TI - Lack of immunoglobulin E response to longstanding strongyloidiasis. PG - 292-4 AB - Patients harbouring worm infections usually have very marked elevations of serum immunoglobulin E (IgE) concentration. However, in a group of twenty ex-Far East prisoners of war with strongyloidiasis only two (10%) had raised levels due to the worm, and these were only moderately elevated. This poor IgE response may be related to the very longstanding nature of the infection (at least 30 years). The patients may have a form of immunological incompetence, or may have become immunologically tolerant to the parasite. FAU - Gill, G V AU - Gill GV FAU - Bell, D R AU - Bell DR FAU - Fifield, R AU - Fifield R LA - eng PT - Journal Article PL - England TA - Clin Exp Immunol JT - Clinical and experimental immunology JID - 0057202 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Chronic Disease MH - Humans MH - Immune Tolerance MH - Immunoglobulin E/*analysis MH - Strongyloidiasis/*immunology MH - Time Factors PMC - PMC1537796 EDAT- 1979/08/01 00:00 MHDA- 1979/08/01 00:01 PMCR- 1980/08/01 CRDT- 1979/08/01 00:00 PHST- 1979/08/01 00:00 [pubmed] PHST- 1979/08/01 00:01 [medline] PHST- 1979/08/01 00:00 [entrez] PHST- 1980/08/01 00:00 [pmc-release] PST - ppublish SO - Clin Exp Immunol. 1979 Aug;37(2):292-4.