PMID- 533284 OWN - NLM STAT- MEDLINE DCOM- 19800425 LR - 20131121 IS - 0003-987X (Print) IS - 0003-987X (Linking) VI - 115 IP - 12 DP - 1979 Dec TI - Subacute cutaneous lupus erythematosus: a cutaneous marker for a distinct lupus erythematosus subset. PG - 1409-15 AB - We have characterized the clinical and laboratory features of 27 patients who had in common a recurring, superficial, nonscarring type of cutaneous lupus erythematosus (LE) that occurred in a characteristic distribution (subacute cutaneous lupus erythematosus [SCLE]). This clinically distinct form of cutaneous LE has not previously been analyzed as a separate entity and thus, its clinical importance has not been fully appreciated. We found that these patients frequently had a mild systemic illness marked by musculoskeletal complaints and serologic abnormalities. Forty-eight percent had systemic LE by American Rheumatism Association criteria; however, none had serious CNS or renal disease. Thus, those with SCLE are a subset of patients with LE who generally have an illness intermediate in severity between discoid LE and severe systemic LE. FAU - Sontheimer, R D AU - Sontheimer RD FAU - Thomas, J R AU - Thomas JR FAU - Gilliam, J N AU - Gilliam JN LA - eng PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Arch Dermatol JT - Archives of dermatology JID - 0372433 RN - 2W4A77YPAN (Fluocinonide) RN - 4QWG6N8QKH (Hydroxychloroquine) RN - 8N3DW7272P (Cyclophosphamide) SB - IM MH - Adult MH - Aged MH - Cyclophosphamide/therapeutic use MH - Diagnosis, Differential MH - Evaluation Studies as Topic MH - Female MH - Fluocinonide/therapeutic use MH - Humans MH - Hydroxychloroquine/therapeutic use MH - Lupus Erythematosus, Discoid/diagnosis MH - Lupus Erythematosus, Systemic/diagnosis/drug therapy/immunology/*pathology MH - Male MH - Middle Aged MH - Skin Diseases/*pathology EDAT- 1979/12/01 00:00 MHDA- 1979/12/01 00:01 CRDT- 1979/12/01 00:00 PHST- 1979/12/01 00:00 [pubmed] PHST- 1979/12/01 00:01 [medline] PHST- 1979/12/01 00:00 [entrez] PST - ppublish SO - Arch Dermatol. 1979 Dec;115(12):1409-15.