PMID- 535725 OWN - NLM STAT- MEDLINE DCOM- 19800523 LR - 20210915 IS - 0016-6731 (Print) IS - 0016-6731 (Linking) VI - 92 IP - 3 DP - 1979 Jul TI - The genetics of hexokinase in a mosquito, Culex pipiens. PG - 903-13 AB - The genetics of hexokinase (HK) variants in a mosquito, Culex pipiens L., was studied using starch gel electrophoresis. Three isozymic forms of HK, all migrating anodally, were present in all three body regions, but in differing proportions. No obvious differences in specificity for three hexose sugars was detected among the three isozymic bands. However, qualitative differences in staining intensity indicate the following order of substrate affinity: glucose greater than fructose greater than mannose. The inheritance of the HK variants is controlled by a pair of co-dominant alleles at a single genetic locus. FAU - Cheng, M L AU - Cheng ML FAU - Hacker, C S AU - Hacker CS LA - eng PT - Journal Article PL - United States TA - Genetics JT - Genetics JID - 0374636 RN - 30237-26-4 (Fructose) RN - EC 2.7.1.1 (Hexokinase) RN - IY9XDZ35W2 (Glucose) RN - PHA4727WTP (Mannose) SB - IM MH - Alleles MH - Animals MH - Culex/*genetics MH - Electrophoresis, Starch Gel MH - Fructose/metabolism MH - Genes, Dominant MH - Genetic Variation MH - Glucose/metabolism MH - Hexokinase/*genetics MH - Mannose/metabolism PMC - PMC1214045 EDAT- 1979/07/01 00:00 MHDA- 1979/07/01 00:01 PMCR- 1979/10/01 CRDT- 1979/07/01 00:00 PHST- 1979/07/01 00:00 [pubmed] PHST- 1979/07/01 00:01 [medline] PHST- 1979/07/01 00:00 [entrez] PHST- 1979/10/01 00:00 [pmc-release] AID - 10.1093/genetics/92.3.903 [doi] PST - ppublish SO - Genetics. 1979 Jul;92(3):903-13. doi: 10.1093/genetics/92.3.903.