PMID- 566472 OWN - NLM STAT- MEDLINE DCOM- 19780901 LR - 20190702 IS - 0038-4348 (Print) IS - 0038-4348 (Linking) VI - 71 IP - 7 DP - 1978 Jul TI - Severe thrombocytopenia after generalized herpes simplex virus-2 (HSV-2) infection. PG - 864-5 AB - Our patient, we believe, experienced a primary HSV-2 infection manifested by fever, malaise, and orogenital mucocutaneous lesions. With resolution of systemic manifestations, and at a time of theorized rise in HSV-2 antibody levels, he had thrombocytopenic purpura which persisted for several weeks. An immune disorder secondary to HSV-2 infection similar to that of postrubella infection is postulated. If this theory is correct, severe immune thrombocytopenic purpura is yet one more of the many observed complications of HSV infection. FAU - Whitaker, J A 3rd AU - Whitaker JA 3rd FAU - Hardison, J E AU - Hardison JE LA - eng PT - Case Reports PT - Journal Article PL - United States TA - South Med J JT - Southern medical journal JID - 0404522 SB - IM MH - Adult MH - Herpes Simplex/*complications MH - Humans MH - Male MH - Purpura, Thrombocytopenic/*etiology EDAT- 1978/07/01 00:00 MHDA- 1978/07/01 00:01 CRDT- 1978/07/01 00:00 PHST- 1978/07/01 00:00 [pubmed] PHST- 1978/07/01 00:01 [medline] PHST- 1978/07/01 00:00 [entrez] AID - 10.1097/00007611-197807000-00035 [doi] PST - ppublish SO - South Med J. 1978 Jul;71(7):864-5. doi: 10.1097/00007611-197807000-00035.