PMID- 59481
OWN - NLM
STAT- MEDLINE
DCOM- 19760902
LR  - 20071115
IS  - 0300-5860 (Print)
IS  - 0300-5860 (Linking)
VI  - 65
IP  - 6
DP  - 1976 Jun
TI  - Assessment of the mid systolic click late systolic murmur syndrome by noninvasive 
      methods.
PG  - 522-33
AB  - In patients with the mid systolic click/late systolic murmur syndrome (MSC/LSM 
      Sy) a ballooning, billowing or aneurysmal protrusion of one or both mitral 
      leaflets has previously been described in angiographic studies. It is accepted 
      that besides angiography noninvasive methods such as dynamic electrocardiography, 
      phonocardiography, apexcardiography and echocardiography can provide valuable 
      information in the diagnosis of this syndrome. Little is known however about 
      diagnostic value and sensitivity of these methods. The dynamic Ecg, recorded 
      during an average of 10 hours, showed in 8/20 patients (40%) one or several 
      significant arrhythmias such as frequent ventricular premature contractions 
      (VPCs) (greater than 12/min), multifocal VPCs, VPCs in a row or ventricular 
      tachycardia, or 2 degrees SA-block. 12/20 patients (60%) showed in the 
      phonocardiogram a movement of the click toward the first heart sound when the 
      patients' position was changed from supine to sitting. In 40% of the patients a 
      double or triple click was recorded. A late systolic bulge in the apexcardiogram 
      was seen in 13/20 patients (65%). In one patient the recording was not 
      successful. Echocardiographic signs of abnormal posterior movement (prolapse) of 
      one or both mitral leaflets were recorded in 15/20 patients (75%). Five 
      echocardiograms did not show any abnormality, but all these cases demonstrated in 
      their apexcardiogram a late systolic bulge. We believe that in patients with the 
      MSC/LSM Sy a mitral valve abnormality can be documented adequately by noninvasive 
      methods.
FAU - Burckhardt, D
AU  - Burckhardt D
FAU - Engel, U R
AU  - Engel UR
FAU - Sefidpar, M
AU  - Sefidpar M
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Z Kardiol
JT  - Zeitschrift fur Kardiologie
JID - 0360430
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Arrhythmias, Cardiac/complications
MH  - Cardiac Complexes, Premature/complications
MH  - Echocardiography
MH  - Electrocardiography
MH  - Female
MH  - *Heart Auscultation
MH  - *Heart Murmurs
MH  - Heart Valve Diseases/complications/*diagnosis
MH  - Humans
MH  - Kinetocardiography
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve/abnormalities
MH  - Phonocardiography
MH  - Posture
MH  - Syndrome
MH  - Tachycardia/complications
MH  - Time Factors
EDAT- 1976/06/01 00:00
MHDA- 1976/06/01 00:01
CRDT- 1976/06/01 00:00
PHST- 1976/06/01 00:00 [pubmed]
PHST- 1976/06/01 00:01 [medline]
PHST- 1976/06/01 00:00 [entrez]
PST - ppublish
SO  - Z Kardiol. 1976 Jun;65(6):522-33.