PMID- 601773
OWN - NLM
STAT- MEDLINE
DCOM- 19780310
LR  - 20190727
IS  - 0040-8727 (Print)
IS  - 0040-8727 (Linking)
VI  - 123
IP  - 3
DP  - 1977 Nov
TI  - Association of human leukocyte antigen (HLA)-B5 and -BW22-J with hepatic 
      cirrhosis of apparently unknown etiology.
PG  - 257-63
AB  - The majority of patients with hepatic cirrhosis in Japan do not have a history of 
      acute hepatitis or alcoholism. Twenty-nine patients with hepatic cirrhosis which 
      were thought as random samples from cirrhotic patients without a history of acute 
      hepatitis or alcoholism were Human Leukocyte Antigen (HLA) typed. Association of 
      HLA-B5 and -BW22-J with hepatic cirrhosis of apparently unknown etiology was 
      found in p less than 0.003, and p less than 0.01, respectively (128 controls). A 
      predisposition linked to HLA-B5 or -BW22-J related gene or genes seems to play a 
      role in the development of hepatic cirrhosis, at least in a substantial part of 
      patients with hepatic cirrhosis of apparently unknown etiology in Japan.
FAU - Ohkubo, A
AU  - Ohkubo A
FAU - Okimoto, K
AU  - Okimoto K
FAU - Iwasaki, Y
AU  - Iwasaki Y
FAU - Kosaka, K
AU  - Kosaka K
FAU - Juji, T
AU  - Juji T
FAU - Tohyama, H
AU  - Tohyama H
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Tohoku J Exp Med
JT  - The Tohoku journal of experimental medicine
JID - 0417355
RN  - 0 (Histocompatibility Antigens)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Female
MH  - Histocompatibility Antigens/*analysis
MH  - Humans
MH  - Liver Cirrhosis/etiology/genetics/*immunology
MH  - Male
MH  - Middle Aged
EDAT- 1977/11/01 00:00
MHDA- 1977/11/01 00:01
CRDT- 1977/11/01 00:00
PHST- 1977/11/01 00:00 [pubmed]
PHST- 1977/11/01 00:01 [medline]
PHST- 1977/11/01 00:00 [entrez]
AID - 10.1620/tjem.123.257 [doi]
PST - ppublish
SO  - Tohoku J Exp Med. 1977 Nov;123(3):257-63. doi: 10.1620/tjem.123.257.