PMID- 6093435
OWN - NLM
STAT- MEDLINE
DCOM- 19841218
LR  - 20190815
IS  - 0001-690X (Print)
IS  - 0001-690X (Linking)
VI  - 70
IP  - 4
DP  - 1984 Oct
TI  - Plasma pattern of adrenocorticotropin and cortisol during electroconvulsive 
      therapy in patients with major depressive illness.
PG  - 361-9
AB  - Thirty-three patients with major depressive illness were treated with 
      electroconvulsive therapy (ECT) and plasma adrenocorticotropin (ACTH), and 
      cortisol levels were measured 30 min before and 1, 5, 15, 30 and 60 min after 
      ECT. There was an immediate release of ACTH with a maximum after 5 min. The 
      maximum cortisol plasma levels were measured 30 min after ECT. No change in ACTH 
      and cortisol concentrations was seen in control experiments when the patients 
      received only anaesthesia. ACTH release was seen in patients treated with ECT in 
      the morning and in the evening. In 15 patients the levels were studied at the 
      first and sixth (last) ECT. ACTH and cortisol levels were significantly higher 
      after the first ECT as compared with the sixth. This alteration in ACTH release 
      might reflect ECT-induced changes in the central monoaminergic transmission with 
      stimulation of beta-adrenergic pathways leading to inhibition of ACTH-release.
FAU - Aperia, B
AU  - Aperia B
FAU - Thoren, M
AU  - Thoren M
FAU - Zettergren, M
AU  - Zettergren M
FAU - Wetterberg, L
AU  - Wetterberg L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Acta Psychiatr Scand
JT  - Acta psychiatrica Scandinavica
JID - 0370364
RN  - 0 (Receptors, Adrenergic)
RN  - 9002-60-2 (Adrenocorticotropic Hormone)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Adrenocorticotropic Hormone/*blood
MH  - Adult
MH  - Aged
MH  - Depressive Disorder/blood/*therapy
MH  - *Electroconvulsive Therapy
MH  - Female
MH  - Humans
MH  - Hydrocortisone/*blood
MH  - Male
MH  - Middle Aged
MH  - Receptors, Adrenergic/physiology
MH  - Time Factors
EDAT- 1984/10/01 00:00
MHDA- 1984/10/01 00:01
CRDT- 1984/10/01 00:00
PHST- 1984/10/01 00:00 [pubmed]
PHST- 1984/10/01 00:01 [medline]
PHST- 1984/10/01 00:00 [entrez]
AID - 10.1111/j.1600-0447.1984.tb01221.x [doi]
PST - ppublish
SO  - Acta Psychiatr Scand. 1984 Oct;70(4):361-9. doi: 
      10.1111/j.1600-0447.1984.tb01221.x.