PMID- 610409
OWN - NLM
STAT- MEDLINE
DCOM- 19780517
LR  - 20151119
IS  - 0301-0546 (Print)
IS  - 0301-0546 (Linking)
VI  - 5
IP  - 6
DP  - 1977 Nov-Dec
TI  - IgE concentration in asthmatic children. Relation to other immunoglobulins, 
      histamine-latex reaction, eosinophilia and skin reactivity.
PG  - 653-8
AB  - Serum concentrations of immunoglobulin E (IgE) were measured in 31 children with 
      bronchial asthma and in 55 healthy children. Among the asthmatic children, 70% 
      had elevated IgE levels, 83% had a low titre of histamine-latex agglutination and 
      80% had blood eosinophilia over 3%. All asthmatic children showed 
      hypersensitivity to one or more allergens; the highest incidence of 
      hypersensitivity was to house dust (38% of asthmatic children), followed by 
      pollens (25%) and vegetable fibers (19%). No relation was observed between serum 
      IgE concentration and the intensity of cutaneous reaction or the number of 
      sensitizing allergens. No significant difference was observed in serum IgE 
      concentration in asthmatic children submitted hyposensitization therapy compared 
      with those who had not received such treatment. It is concluded that IgE 
      determination may be valuable for differential diagnosis between allergic and non 
      allergic asthma and that IgE measurement should be considered as a complementary 
      test in the investigation of allergy.
FAU - Barbera, G
AU  - Barbera G
FAU - Munoz-Lopez, F
AU  - Munoz-Lopez F
FAU - Cruz-Hernandez, M
AU  - Cruz-Hernandez M
FAU - Torralba, A
AU  - Torralba A
LA  - eng
PT  - Journal Article
PL  - Singapore
TA  - Allergol Immunopathol (Madr)
JT  - Allergologia et immunopathologia
JID - 0370073
RN  - 37341-29-0 (Immunoglobulin E)
RN  - 820484N8I3 (Histamine)
SB  - IM
MH  - Asthma/*immunology
MH  - Cell Count
MH  - Child
MH  - Child, Preschool
MH  - Eosinophils/analysis
MH  - Female
MH  - Histamine
MH  - Humans
MH  - Immunoglobulin E/*analysis
MH  - Latex Fixation Tests
MH  - Male
MH  - Skin Tests
EDAT- 1977/11/01 00:00
MHDA- 1977/11/01 00:01
CRDT- 1977/11/01 00:00
PHST- 1977/11/01 00:00 [pubmed]
PHST- 1977/11/01 00:01 [medline]
PHST- 1977/11/01 00:00 [entrez]
PST - ppublish
SO  - Allergol Immunopathol (Madr). 1977 Nov-Dec;5(6):653-8.