PMID- 6117187
OWN - NLM
STAT- MEDLINE
DCOM- 19811222
LR  - 20041117
IS  - 0300-8967 (Print)
IS  - 0300-8967 (Linking)
VI  - 81
IP  - 2
DP  - 1981 Mar-Apr
TI  - The use of long-acting neuroleptics in the acute psychoses.
PG  - 173-81
AB  - Out of 120 inpatients treated with long-acting neuroleptics (LANs) between May 
      1977 and May 1978, the authors have selected 43 patients with clear-cut acute 
      psychotic symptoms and high doses or frequent injections of fluphenazine 
      decanoate: 19 schizophrenics, 13 schizoaffective psychoses and 11 manics. The 
      average single dosage was 32 to 37 mg depending on the diagnostic category; the 
      average weekly dosage was 45 to 55 mg; the average frequency of injections was 
      one every 5 to 7 days. Drug combinations could be greater reduced. On discharge, 
      all long-acting treatments were discontinued in manics, against some 60% of 
      schizophrenics and schizoaffective psychoses. Among the advantages of LANs, the 
      authors mention optimum pharmacokinetics (hence, lower doses), increased 
      compliance from the part of the patient (less hostility thanks to decreased 
      administrations than with oral medications), avoidance of cases of intestinal 
      malabsorption, lowered financial burden (less treatment units, fewer admissions, 
      shorter duration of hospitalization, less polypharmacy.
FAU - Cassano, G B
AU  - Cassano GB
FAU - Placidi, G F
AU  - Placidi GF
LA  - eng
PT  - Journal Article
PL  - Belgium
TA  - Acta Psychiatr Belg
JT  - Acta psychiatrica Belgica
JID - 0247037
RN  - 0 (Antipsychotic Agents)
RN  - 0 (Delayed-Action Preparations)
SB  - IM
MH  - Acute Disease
MH  - Antipsychotic Agents/*administration & dosage
MH  - Bipolar Disorder/drug therapy
MH  - Delayed-Action Preparations
MH  - Drug Therapy, Combination
MH  - Humans
MH  - Psychotic Disorders/*drug therapy
MH  - Schizophrenia/drug therapy
MH  - Time Factors
EDAT- 1981/03/01 00:00
MHDA- 1981/03/01 00:01
CRDT- 1981/03/01 00:00
PHST- 1981/03/01 00:00 [pubmed]
PHST- 1981/03/01 00:01 [medline]
PHST- 1981/03/01 00:00 [entrez]
PST - ppublish
SO  - Acta Psychiatr Belg. 1981 Mar-Apr;81(2):173-81.