PMID- 6136181 OWN - NLM STAT- MEDLINE DCOM- 19830920 LR - 20210806 IS - 0195-6108 (Print) IS - 1936-959X (Electronic) IS - 0195-6108 (Linking) VI - 4 IP - 3 DP - 1983 May-Jun TI - CT of the pituitary gland in multiple endocrine neoplasia type 1 syndrome. PG - 813-5 AB - Multiple endocrine neoplasia type 1 (MEN-1) is an autosomal dominant disease involving tumors of the parathyroid, pancreas, and pituitary glands. Over 50% of the patients with this syndrome will have involvement of the pituitary gland. Computed tomography (CT) of the head was performed in 21 of 42 patients with the clinical diagnosis of MEN-1. CT demonstrated pituitary abnormalities in 15 patients, 13 of whom had pituitary endocrine dysfunction. The most common endocrinopathy was hyperprolactinemia, documented in nine patients. Hypopituitarism due to nonfunctional adenoma was found in two patients, and acromegaly and Cushing disease in individual cases. The appearance of the pituitary gland in CT evaluation of the sella in patients with MEN-1 is presented. FAU - Rieth, K G AU - Rieth KG FAU - Brody, S A AU - Brody SA LA - eng PT - Journal Article PL - United States TA - AJNR Am J Neuroradiol JT - AJNR. American journal of neuroradiology JID - 8003708 RN - 9002-62-4 (Prolactin) SB - IM MH - Adenoma/diagnostic imaging MH - Humans MH - Multiple Endocrine Neoplasia/*diagnostic imaging MH - Pituitary Neoplasms/*diagnostic imaging MH - Prolactin/metabolism MH - *Tomography, X-Ray Computed PMC - PMC8334896 EDAT- 1983/05/01 00:00 MHDA- 1983/05/01 00:01 PMCR- 1984/05/01 CRDT- 1983/05/01 00:00 PHST- 1983/05/01 00:00 [pubmed] PHST- 1983/05/01 00:01 [medline] PHST- 1983/05/01 00:00 [entrez] PHST- 1984/05/01 00:00 [pmc-release] PST - ppublish SO - AJNR Am J Neuroradiol. 1983 May-Jun;4(3):813-5.