PMID- 6140821 OWN - NLM STAT- MEDLINE DCOM- 19840214 LR - 20121115 IS - 0300-8967 (Print) IS - 0300-8967 (Linking) VI - 83 IP - 4 DP - 1983 Jul-Aug TI - Teflutixol (Lu 10-022): a new thioxanthene derivative with antipsychotic properties. A pilot study. PG - 397-406 AB - A new thioxanthene derivative, teflutixol (Lu 10-022) has been administered for 4 weeks to 21 patients [12 schizophrenics, 6 patients with obsessive, compulsive neurosis (OCN), 2 patients with affective psychosis (AP), and one patient with paranoic reactions (PR)]. The maximum daily dose varied between 0.5 mg and 4 mg administered once in the morning. Fifteen of the patients received 1 mg or less daily. Based upon weekly assessments by the BPRS as well as a global evaluation all 4 groups showed a clear amelioration of the scores, and for both the schizophrenics and the patients with OCN this was highly significant [student's t (p less than 0.001)]. FAU - Botte, L AU - Botte L LA - eng PT - Journal Article PL - Belgium TA - Acta Psychiatr Belg JT - Acta psychiatrica Belgica JID - 0247037 RN - 0 (Antipsychotic Agents) RN - 0 (Thioxanthenes) RN - 1O8A15G935 (teflutixol) SB - IM MH - Adult MH - Antipsychotic Agents/*administration & dosage MH - Drug Evaluation MH - Female MH - Humans MH - Male MH - Mental Disorders/*drug therapy MH - Middle Aged MH - Obsessive-Compulsive Disorder/drug therapy MH - Schizophrenia/drug therapy MH - Thioxanthenes/*administration & dosage EDAT- 1983/07/01 00:00 MHDA- 1983/07/01 00:01 CRDT- 1983/07/01 00:00 PHST- 1983/07/01 00:00 [pubmed] PHST- 1983/07/01 00:01 [medline] PHST- 1983/07/01 00:00 [entrez] PST - ppublish SO - Acta Psychiatr Belg. 1983 Jul-Aug;83(4):397-406.