PMID- 6143550
OWN - NLM
STAT- MEDLINE
DCOM- 19840524
LR  - 20190704
IS  - 0004-0010 (Print)
IS  - 0004-0010 (Linking)
VI  - 119
IP  - 5
DP  - 1984 May
TI  - Surgical management of hyperinsulinemic hypoglycemia in children.
PG  - 520-5
AB  - Nineteen children underwent subtotal pancreatectomy for hyperinsulinemic 
      hypoglycemia. Of the four who were older than 10 years of age at onset of 
      symptoms, three had islet adenomas, and one had endocrine cell dysplasia (ECD). 
      The two patients with multiple adenomas had a family history of multiple 
      endocrine neoplasia, type 1 (MEN 1). Of the 15 who were younger than 1 year of 
      age at onset of symptoms, 12 had ECD alone, and three had ECD with adenomatosis. 
      Four children required a second surgical procedure and near-total pancreatectomy 
      because of persistent hypoglycemia. All 19 patients' conditions improved, with no 
      postsurgical complications. After near-total pancreatectomy, all four patients 
      were treated for fat malabsorption, but only two required insulin because of 
      secondary diabetes mellitus. We concluded that subtotal pancreatectomy is a safe, 
      effective adjunct to the treatment of children with hyperinsulinemic 
      hypoglycemia.
FAU - Simmons, P S
AU  - Simmons PS
FAU - Telander, R L
AU  - Telander RL
FAU - Carney, J A
AU  - Carney JA
FAU - Wold, L E
AU  - Wold LE
FAU - Haymond, M W
AU  - Haymond MW
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Arch Surg
JT  - Archives of surgery (Chicago, Ill. : 1960)
JID - 9716528
SB  - IM
MH  - Adenoma/*surgery
MH  - Adolescent
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Humans
MH  - Hyperinsulinism/*surgery
MH  - Hypoglycemia/*surgery
MH  - Infant
MH  - Male
MH  - Multiple Endocrine Neoplasia/surgery
MH  - *Pancreatectomy/methods
MH  - Pancreatic Neoplasms/*surgery
EDAT- 1984/05/01 00:00
MHDA- 1984/05/01 00:01
CRDT- 1984/05/01 00:00
PHST- 1984/05/01 00:00 [pubmed]
PHST- 1984/05/01 00:01 [medline]
PHST- 1984/05/01 00:00 [entrez]
AID - 10.1001/archsurg.1984.01390170020005 [doi]
PST - ppublish
SO  - Arch Surg. 1984 May;119(5):520-5. doi: 10.1001/archsurg.1984.01390170020005.