PMID- 6143877
OWN - NLM
STAT- MEDLINE
DCOM- 19840530
LR  - 20190611
IS  - 0140-6736 (Print)
IS  - 0140-6736 (Linking)
VI  - 1
IP  - 8383
DP  - 1984 Apr 28
TI  - Bladder cancer in the aluminium industry.
PG  - 947-50
AB  - The incidence of bladder cancer is unusually high in aluminium smelter workers. 
      An epidemiological study showed that workers in Soderberg potrooms are at highest 
      risk for bladder cancer, the adjusted overall relative risk being 2.39 
      (1.34-4.28). Exposure to polycyclic aromatic hydrocarbons, of which benz(a)pyrene 
      (BaP) served as an indicator, seems to be the causative factor. The relative risk 
      was evaluated at 12.38 for workers with 20 or more equivalent years of BaP 
      exposure. Cigarette smoking contributed significantly to the appearance of 
      bladder cancer in the population studied. There is a synergistic effect when 
      cigarette smoking and BaP exposure are combined; the numbers in our population 
      are too small to determine whether this interaction effect is multiplicative or 
      additive. It is concluded that bladder cancer is associated with aluminium 
      smelting (primarily with the Soderberg process).
FAU - Theriault, G
AU  - Theriault G
FAU - Tremblay, C
AU  - Tremblay C
FAU - Cordier, S
AU  - Cordier S
FAU - Gingras, S
AU  - Gingras S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Lancet
JT  - Lancet (London, England)
JID - 2985213R
RN  - 0 (Benzopyrenes)
RN  - CPD4NFA903 (Aluminum)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aluminum/*poisoning
MH  - Benzopyrenes/poisoning
MH  - Carcinoma, Basal Cell/chemically induced/epidemiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Occupational Diseases/*chemically induced/epidemiology
MH  - Occupations
MH  - Quebec
MH  - Risk
MH  - Smoking
MH  - Urinary Bladder Neoplasms/*chemically induced/epidemiology
EDAT- 1984/04/28 00:00
MHDA- 1984/04/28 00:01
CRDT- 1984/04/28 00:00
PHST- 1984/04/28 00:00 [pubmed]
PHST- 1984/04/28 00:01 [medline]
PHST- 1984/04/28 00:00 [entrez]
AID - S0140-6736(84)92399-7 [pii]
AID - 10.1016/s0140-6736(84)92399-7 [doi]
PST - ppublish
SO  - Lancet. 1984 Apr 28;1(8383):947-50. doi: 10.1016/s0140-6736(84)92399-7.