PMID- 6154805
OWN - NLM
STAT- MEDLINE
DCOM- 19800712
LR  - 20200724
IS  - 0022-538X (Print)
IS  - 1098-5514 (Electronic)
IS  - 0022-538X (Linking)
VI  - 34
IP  - 1
DP  - 1980 Apr
TI  - Alterations of a mouse mammary tumor virus glycoprotein with interferon 
      treatment.
PG  - 225-33
AB  - The effects of exogenous mouse interferon on the MJY-alpha mammary tumor cell 
      line chronically infected with mouse mammary tumor virus (MMTV) were examined. 
      Interferon at concentrations of 25 to 2,000 IU/ml in culture medium did not alter 
      the growth rate or morphology of the cell layers. Electron microscopic 
      examination of interferon-treated cells indicated a decrease in the numbers of 
      A-type and budding B-type particles of MMTV. However, the levels of extracellular 
      MMTV virions in the culture supernatants were not significantly reduced. Profiles 
      of MMTV glycoproteins and nonglycosylated polypeptides obtained by sodium dodecyl 
      sulfate-polyacrylamide gel electrophoresis of virions purified from 
      interferon-treated cultures revealed increases in the relative levels of the 
      60,000-dalton glycoprotein, gp60.
FAU - Yagi, M J
AU  - Yagi MJ
FAU - King, N W Jr
AU  - King NW Jr
FAU - Bekesi, J G
AU  - Bekesi JG
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - J Virol
JT  - Journal of virology
JID - 0113724
RN  - 0 (Glycoproteins)
RN  - 0 (Viral Proteins)
RN  - 9008-11-1 (Interferons)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Animals
MH  - Cell Division/drug effects
MH  - Cell Line
MH  - Glycoproteins/*biosynthesis
MH  - Hydrocortisone/pharmacology
MH  - Interferons/*pharmacology
MH  - Mammary Neoplasms, Experimental
MH  - Mammary Tumor Virus, Mouse/*growth & development/metabolism
MH  - Mice
MH  - Molecular Weight
MH  - Viral Proteins/*biosynthesis
PMC - PMC288688
EDAT- 1980/04/01 00:00
MHDA- 2001/03/28 10:01
PMCR- 1980/04/01
CRDT- 1980/04/01 00:00
PHST- 1980/04/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1980/04/01 00:00 [entrez]
PHST- 1980/04/01 00:00 [pmc-release]
AID - 10.1128/JVI.34.1.225-233.1980 [doi]
PST - ppublish
SO  - J Virol. 1980 Apr;34(1):225-33. doi: 10.1128/JVI.34.1.225-233.1980.