PMID- 6162127
OWN - NLM
STAT- MEDLINE
DCOM- 19810424
LR  - 20180214
IS  - 0302-282X (Print)
IS  - 0302-282X (Linking)
VI  - 7
IP  - 1
DP  - 1981
TI  - Biochemistry of the augmenting-reducing response in visual evoked potentials.
PG  - 1-8
AB  - The augmenting-reducing response in visual evoked potentials (VEP) has between 
      shown to be a useful tool in psychiatric research. A series of studies has been 
      devoted to the search for the biochemical basis of this phenomenon. An augmenter 
      response in VEP is shown to be clearly related to low levels of endorphins, 
      5-HIAA and homovanillic acid in CSF and to low serum-dopamine-beta-hydroxylase 
      activity, while no significant relationship was found with 
      4-hydroxy-3-methoxyphenylethylene glycol or tryptophan in CSF or MAO in 
      thrombocytes. The results indicate that an augmenter response in VEP is related 
      to low activity in the serotoninergic, dopaminergic and endophinergic pathways in 
      CNS.
FAU - von Knorring, L
AU  - von Knorring L
FAU - Perris, C
AU  - Perris C
LA  - eng
PT  - Journal Article
PL  - Switzerland
TA  - Neuropsychobiology
JT  - Neuropsychobiology
JID - 7512895
RN  - 0 (Endorphins)
RN  - 534-82-7 (Methoxyhydroxyphenylglycol)
RN  - 54-16-0 (Hydroxyindoleacetic Acid)
RN  - 8DUH1N11BX (Tryptophan)
RN  - EC 1.14.17.1 (Dopamine beta-Hydroxylase)
RN  - EC 1.4.3.4 (Monoamine Oxidase)
RN  - X77S6GMS36 (Homovanillic Acid)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blood Platelets/enzymology
MH  - Dopamine beta-Hydroxylase/blood
MH  - Endorphins/cerebrospinal fluid
MH  - Evoked Potentials
MH  - Female
MH  - Homovanillic Acid/cerebrospinal fluid
MH  - Humans
MH  - Hydroxyindoleacetic Acid/cerebrospinal fluid
MH  - Male
MH  - Mental Disorders/*physiopathology
MH  - Methoxyhydroxyphenylglycol/cerebrospinal fluid
MH  - Middle Aged
MH  - Monoamine Oxidase/blood
MH  - Pain, Intractable/*physiopathology
MH  - Tryptophan/cerebrospinal fluid
MH  - Visual Pathways/*physiopathology
EDAT- 1981/01/01 00:00
MHDA- 1981/01/01 00:01
CRDT- 1981/01/01 00:00
PHST- 1981/01/01 00:00 [pubmed]
PHST- 1981/01/01 00:01 [medline]
PHST- 1981/01/01 00:00 [entrez]
AID - 10.1159/000117825 [doi]
PST - ppublish
SO  - Neuropsychobiology. 1981;7(1):1-8. doi: 10.1159/000117825.