PMID- 6164541
OWN - NLM
STAT- MEDLINE
DCOM- 19810720
LR  - 20190721
IS  - 0013-4694 (Print)
IS  - 0013-4694 (Linking)
VI  - 51
IP  - 4
DP  - 1981 Apr
TI  - Bed-time food supplements and sleep: effects of different carbohydrate levels.
PG  - 426-33
AB  - Blood glucose levels were altered during sleep by means of manipulating 
      carbohydrate (CHO) intake through bed-time food supplements. Protein and fat 
      intake were minimally affected. Subjects underwent all conditions in a balanced 
      designed. A high CHO condition resulted in significantly reduced stages 1 + 0 
      sleep over the whole night and significantly increased REM sleep during the first 
      half of the night; there seemed to be a reciprocity between these two changes. 
      High CHO also produced a whole-night significant decrease in stages 4 sleep, 
      which persisted into the recovery night. Few significant differences between the 
      other conditions of low and zero CHO were found. Sleep onset was not affected. It 
      was concluded that relatively high blood glucose levels were required to alter 
      sleep, and perhaps lead to more 'restful' sleep. The present findings were 
      similar to those of related studies. The REM sleep changes were discussed in 
      relation to increases in brain serotonin synthesis mediated by elevated blood 
      glucose levels.
FAU - Porter, J M
AU  - Porter JM
FAU - Horne, J A
AU  - Horne JA
LA  - eng
PT  - Journal Article
PL  - Ireland
TA  - Electroencephalogr Clin Neurophysiol
JT  - Electroencephalography and clinical neurophysiology
JID - 0375035
RN  - 0 (Blood Glucose)
RN  - 0 (Carbohydrates)
SB  - IM
MH  - Adult
MH  - Blood Glucose/analysis
MH  - Carbohydrates/*blood/pharmacology
MH  - *Eating
MH  - Electroencephalography
MH  - Humans
MH  - Male
MH  - Sleep/drug effects/*physiology
MH  - Sleep, REM/drug effects/physiology
MH  - Time Factors
EDAT- 1981/04/01 00:00
MHDA- 1981/04/01 00:01
CRDT- 1981/04/01 00:00
PHST- 1981/04/01 00:00 [pubmed]
PHST- 1981/04/01 00:01 [medline]
PHST- 1981/04/01 00:00 [entrez]
AID - 0013-4694(81)90106-1 [pii]
AID - 10.1016/0013-4694(81)90106-1 [doi]
PST - ppublish
SO  - Electroencephalogr Clin Neurophysiol. 1981 Apr;51(4):426-33. doi: 
      10.1016/0013-4694(81)90106-1.