PMID- 6165664
OWN - NLM
STAT- MEDLINE
DCOM- 19810820
LR  - 20061115
IS  - 0367-6102 (Print)
IS  - 0367-6102 (Linking)
VI  - 55
IP  - 5
DP  - 1980 Sep
TI  - [Studies on establishment and maintenance of persistent infection with measles 
      virus in NC-37 cell. II. Effect of DNA-synthesis-suppressing factor (DSF) on the 
      production of interferon in NC-37 cell infected with measles virus (author's 
      transl)].
PG  - 441-6
AB  - The attenuated strain of measles viruses, Schwarz, CAM-70, or subacute sclerosing 
      panencephalitis (SSPE) virus of measles viruses, Halle, Mantooth was good 
      interferon inducer, but the virulent strain, Edmonston, Toyoshima induced few 
      amount of interferon or not. Furthermore, an inverse relationship seemed to exist 
      between the ability to induce interferon and DNA synthesis suppressing factor 
      (DSF). The attenuated strain or SSPE virus which had not a capacity to produce 
      DSF could induce interferon and establish persistent infection in human lymphoid 
      cell NC-37, while virulent strain did not induce interferon but DSF. Maximum 
      yield of progeny virus was precede the detection of interferon in culture fluids. 
      A persistently infected cells also produced continuously interferon and progeny 
      virus. It is demonstrated that DSF suppressed interferon production by infection 
      of measles virus and that DSF had not an activity like interferon.
FAU - Fujii, N
AU  - Fujii N
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Hokkaido Igaku Zasshi
JT  - [Hokkaido igaku zasshi] The Hokkaido journal of medical science
JID - 17410290R
RN  - 9007-49-2 (DNA)
RN  - 9008-11-1 (Interferons)
SB  - IM
MH  - Cells, Cultured
MH  - DNA/*antagonists & inhibitors/*biosynthesis/physiology
MH  - Humans
MH  - Interferons/*biosynthesis
MH  - Lymphocytes/*metabolism
MH  - Measles virus/*physiology
EDAT- 1980/09/01 00:00
MHDA- 1980/09/01 00:01
CRDT- 1980/09/01 00:00
PHST- 1980/09/01 00:00 [pubmed]
PHST- 1980/09/01 00:01 [medline]
PHST- 1980/09/01 00:00 [entrez]
PST - ppublish
SO  - Hokkaido Igaku Zasshi. 1980 Sep;55(5):441-6.