PMID- 6178616 OWN - NLM STAT- MEDLINE DCOM- 19820924 LR - 20190629 IS - 0014-4754 (Print) IS - 0014-4754 (Linking) VI - 38 IP - 5 DP - 1982 May 15 TI - Effect of des-Tyr1-gamma-endorphin on serotonin metabolism in rat brain regions. PG - 598-9 AB - Intracerebroventricular (i.c.v.) administration of des-Tyr1-gamma-endorphin (0.1 and 1.0 microgram) caused a decrease of the serotonin (5-HT) concentration of the hippocampus. The concentration of 5-HIAA and the pargyline-induced alterations in 5-HT and 5-HIAA were not affected. No effects were noticed in other brain regions. FAU - Kurachi, M AU - Kurachi M FAU - Versteeg, D H AU - Versteeg DH FAU - Van Ree, J M AU - Van Ree JM FAU - Westernberg, H G AU - Westernberg HG FAU - Van Praag, H M AU - Van Praag HM LA - eng PT - Journal Article PL - Switzerland TA - Experientia JT - Experientia JID - 0376547 RN - 0 (Endorphins) RN - 0 (Peptide Fragments) RN - 333DO1RDJY (Serotonin) RN - 54-16-0 (Hydroxyindoleacetic Acid) RN - 67810-56-4 (gamma-endorphin, des-Tyr(1)-) RN - 9MV14S8G3E (Pargyline) SB - IM MH - Animals MH - Brain/drug effects/*metabolism MH - Endorphins/*pharmacology MH - Hippocampus/metabolism MH - Hydroxyindoleacetic Acid/metabolism MH - Male MH - Pargyline/pharmacology MH - Peptide Fragments/*pharmacology MH - Rats MH - Rats, Inbred Strains MH - Serotonin/*metabolism EDAT- 1982/05/15 00:00 MHDA- 1982/05/15 00:01 CRDT- 1982/05/15 00:00 PHST- 1982/05/15 00:00 [pubmed] PHST- 1982/05/15 00:01 [medline] PHST- 1982/05/15 00:00 [entrez] AID - 10.1007/BF02327070 [doi] PST - ppublish SO - Experientia. 1982 May 15;38(5):598-9. doi: 10.1007/BF02327070.