PMID- 6178783
OWN - NLM
STAT- MEDLINE
DCOM- 19820924
LR  - 20061115
IS  - 0386-2887 (Print)
IS  - 0386-2887 (Linking)
VI  - 11
IP  - 4
DP  - 1981 Dec
TI  - [Incidence and prognostic implication of repetitive ventricular premature 
      contractions detected by Holter monitoring (author's transl)].
PG  - 1215-22
AB  - Incidence and prognostic significance of repetitive ventricular premature 
      contractions in various cardiac diseases were evaluated retrospectively with 593 
      consecutive patients referred for the 24-hour continuous electrocardiographic 
      monitoring (Holter monitoring). Primary cardiac diagnoses for 308 patients with 
      structural heart diseases included previous myocardial infarction (MI) in 151 
      patients, angina pectoris in 34, congestive cardiomyopathy (COCM) in 21, valvular 
      heart disease in 29, hypertensive heart disease (HHD) in 18, conduction 
      disturbance in 28, and other cardiovascular abnormalities in 17 patients. Other 
      285 patients (48%) had no known structural heart disease. Repetitive ventricular 
      premature contractions (VPCs) was defined as the occurrence of self-terminating 
      two (couplet), three (triplet) or more consecutive VPCs without associated 
      hemodynamic sequelae. Holter monitoring was done with simultaneous two-channel 
      recordings. Repetitive VPCs were seen in 96 patients; 17% of patients with MI, 
      52% of COCM and 7% of no structural hart disease. Among 308 patients with 
      structural heart disease, 91 had congestive heart failure and 42% of these had 
      repetitive VPCs, whereas only 17% of patients without congestive heart failure 
      had repetitive VPCs. Coronary arteriographic and ventriculographic findings were 
      reviewed in 91 patients with previous MI. Neither the degree of coronary artery 
      involvements nor left ventricular ejection fraction had influence on the 
      occurrence of repetitive VPCs. Four hundreds and sixty-nine patients under the 
      age of 69 years were followed from 6 to 36 months (mean 19 months). Thirteen 
      patients including 5 cases with MI (4% of the cases with MI), 4 with COCM (21% of 
      COCM) and 4 with other structural heart disease (4% of other disease) died 
      suddenly in the follow-up period. In the patients followed, 72 had repetitive 
      VPCs and 9 of them died suddenly. These 9 patients consisted of 4 patients with 
      MI (25% of the cases with MI having repetitive VPCs), 4 with COCM (40% of COCM) 
      and 1 with other structural heart disease (3% of other disease). Thus, patients 
      with MI or COCM had higher incidence of repetitive VPCs and they are at a high 
      risk for sudden cardiac death.
FAU - Chino, M
AU  - Chino M
FAU - Hara, Y
AU  - Hara Y
FAU - Fujii, I
AU  - Fujii I
FAU - Nakamura, Y
AU  - Nakamura Y
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - J Cardiogr
JT  - Journal of cardiography
JID - 7801085
SB  - IM
MH  - Aged
MH  - Angina Pectoris/complications
MH  - Cardiac Complexes, Premature/*diagnosis
MH  - Cardiomyopathies/complications
MH  - Death, Sudden/*etiology
MH  - Electrocardiography/methods
MH  - Follow-Up Studies
MH  - Humans
MH  - Monitoring, Physiologic
MH  - Myocardial Infarction/complications
MH  - Prognosis
EDAT- 1981/12/01 00:00
MHDA- 1981/12/01 00:01
CRDT- 1981/12/01 00:00
PHST- 1981/12/01 00:00 [pubmed]
PHST- 1981/12/01 00:01 [medline]
PHST- 1981/12/01 00:00 [entrez]
PST - ppublish
SO  - J Cardiogr. 1981 Dec;11(4):1215-22.