PMID- 6208875 OWN - NLM STAT- MEDLINE DCOM- 19841218 LR - 20061115 IS - 0003-911X (Print) IS - 0003-911X (Linking) VI - 54 IP - 5 DP - 1984 TI - [Tumor markers (alpha 2-macroglobulin, secretory immunoglobulin A, pregnancy-associated alpha 2-glycoprotein) in the serum of patients with bronchial carcinoma]. PG - 391-8 AB - Concentration of alpha 2-macroglobulin (AMG), pregnancy associated-alpha 2-glycoprotein (alpha 2-PAG, PZ) secretory immunoglobulin A (S-IgA), pregnancy specific-beta 1-glycoprotein (SP1) and immunoglobulin E (IgE) were estimated in serum samples of 88 patients with lung cancer of stages, II-IV. The proteins were determined by means of the single radial immunodiffusion and the rocket immunoelectrophoresis. AMG and S-IgA serum concentrations of the cancer group compared with those of the control group, were increased significantly. AMG (control group: means = 1,43 g/l; s = 0,999; tumor group: means = 4,37 g/l; s = 1,758); S-IgA (control group: means = 37 mg/l; s = 16,6; tumor group: means = 48 mg/l; s = 24,2). PZ was found only in 52% of the patients with lung cancer by means of the rocket immunoelectrophoresis. The difference between the tumour and the control group was not significant. IgE could be detected only in one case with lung cancer (IgE = 2950 IU/ml). It was not possible to detect SP1 by means of the single radial immunodiffusion in serum samples of lung cancer patients. FAU - Briese, V AU - Briese V FAU - Willroth, P O AU - Willroth PO FAU - Brock, J AU - Brock J FAU - Straube, W AU - Straube W LA - ger PT - English Abstract PT - Journal Article TT - Zum Verhalten einiger Tumormarker (alpha 2-Makroglobulin, sekretorisches Immunoglobulin A, schwangerschaftsassoziiertes alpha 2-Glykoprotein) im Serum von Patienten mit Bronchialkarzinom. PL - Germany TA - Arch Geschwulstforsch JT - Archiv fur Geschwulstforschung JID - 0372411 RN - 0 (Immunoglobulin A, Secretory) RN - 0 (Pregnancy Proteins) RN - 0 (alpha-Macroglobulins) SB - IM MH - Adult MH - Aged MH - Carcinoma, Bronchogenic/*blood MH - Female MH - Humans MH - Immunoglobulin A, Secretory/*analysis MH - Lung Neoplasms/*blood MH - Male MH - Middle Aged MH - Pregnancy Proteins/*analysis MH - alpha-Macroglobulins/*analysis EDAT- 1984/01/01 00:00 MHDA- 1984/01/01 00:01 CRDT- 1984/01/01 00:00 PHST- 1984/01/01 00:00 [pubmed] PHST- 1984/01/01 00:01 [medline] PHST- 1984/01/01 00:00 [entrez] PST - ppublish SO - Arch Geschwulstforsch. 1984;54(5):391-8.