PMID- 6212085 OWN - NLM STAT- MEDLINE DCOM- 19820924 LR - 20131121 IS - 0006-3029 (Print) IS - 0006-3029 (Linking) VI - 27 IP - 3 DP - 1982 May-Jun TI - [Acridine orange inhibition of the ATPase activity of myosin and its fragments]. PG - 368-70 AB - The cation dye acridine orange (AO) was shown to inhibit ATPase activity of myosin, DTNB-myosin and heavy meromyosin and not to influence that of EDTA-S-1 at low ionic force. The inhibiting effect is concerned with the presence of KCl in solution. The allosteric influence of AO on myosin ATPase activity is discussed and dependence of this effect on charge distribution on the surface of the protein molecule is considered. FAU - Filatova, L G AU - Filatova LG FAU - Shtrankfel'd, I G AU - Shtrankfel'd IG FAU - Levitskii, D I AU - Levitskii DI FAU - Esipova, N G AU - Esipova NG LA - rus PT - English Abstract PT - Journal Article TT - Ingibirovanie ATFaznoi aktivnosti miozina i ego fragmentov akridinovym oranzhevym. PL - Russia (Federation) TA - Biofizika JT - Biofizika JID - 0372666 RN - 0 (Myosin Subfragments) RN - 9BZQ3U62JX (Dithionitrobenzoic Acid) RN - EC 3.6.1.- (Adenosine Triphosphatases) RN - EC 3.6.4.1 (Myosins) RN - F30N4O6XVV (Acridine Orange) SB - IM MH - Acridine Orange/*pharmacology MH - Adenosine Triphosphatases/*antagonists & inhibitors MH - Animals MH - Dithionitrobenzoic Acid/pharmacology MH - Kinetics MH - Myosin Subfragments/metabolism MH - Myosins/*antagonists & inhibitors MH - Rabbits EDAT- 1982/05/01 00:00 MHDA- 1982/05/01 00:01 CRDT- 1982/05/01 00:00 PHST- 1982/05/01 00:00 [pubmed] PHST- 1982/05/01 00:01 [medline] PHST- 1982/05/01 00:00 [entrez] PST - ppublish SO - Biofizika. 1982 May-Jun;27(3):368-70.