PMID- 6214587
OWN - NLM
STAT- MEDLINE
DCOM- 19821203
LR  - 20031114
IS  - 0022-1767 (Print)
IS  - 0022-1767 (Linking)
VI  - 129
IP  - 5
DP  - 1982 Nov
TI  - Binding of immunoglobulin E to the receptor on rat peritoneal macrophages.
PG  - 2004-8
AB  - The binding of radiolabeled monomers and chemically cross-linked dimers of rat 
      immunoglobulin E (IgE) to peritoneal macrophages of rats was characterized. With 
      either form, 40,000 to 50,000 molecules of IgE were specifically bound per cell 
      under conditions where no endocytosis occurred. Monomeric IgE dissociated from 
      macrophages within minutes, whereas dimers of IgE had a much slower rate of 
      dissociation. Denatured rat IgE or native human IgE failed to inhibit the 
      binding, but mouse IgE and, to a limited extent, rat IgG did. Oligomers of IgE by 
      virtue of their tighter association with the receptor should prove useful in 
      isolation of the receptor.
FAU - Finbloom, D S
AU  - Finbloom DS
FAU - Metzger, H
AU  - Metzger H
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Immunol
JT  - Journal of immunology (Baltimore, Md. : 1950)
JID - 2985117R
RN  - 0 (Receptors, IgE)
RN  - 0 (Receptors, Immunologic)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Animals
MH  - Antibody Specificity
MH  - Ascitic Fluid/*cytology
MH  - Immunoglobulin E/*metabolism
MH  - Immunologic Techniques
MH  - Macrophages/*metabolism
MH  - Rats
MH  - Rats, Inbred F344
MH  - Rats, Inbred Lew
MH  - Receptors, IgE
MH  - Receptors, Immunologic/*analysis
EDAT- 1982/11/01 00:00
MHDA- 1982/11/01 00:01
CRDT- 1982/11/01 00:00
PHST- 1982/11/01 00:00 [pubmed]
PHST- 1982/11/01 00:01 [medline]
PHST- 1982/11/01 00:00 [entrez]
PST - ppublish
SO  - J Immunol. 1982 Nov;129(5):2004-8.