PMID- 6279247
OWN - NLM
STAT- MEDLINE
DCOM- 19820614
LR  - 20190614
IS  - 0006-8993 (Print)
IS  - 0006-8993 (Linking)
VI  - 255
IP  - 3
DP  - 1982 Mar
TI  - Development of spontaneous neuronal activity in the caudate nucleus, globus 
      pallidus-entopeduncular nucleus, and substantia nigra of the cat.
PG  - 429-41
AB  - Spontaneous single unit activity was obtained from caudate (Cd), globus 
      pallidus-entopeduncular nucleus (GP-Ento), and substantia nigra (SN) neurons in 
      kittens of 1-60 days of age and adult cats. Five developmental trends were found 
      in the spontaneous firing patterns of these neurons: (1) overall mean interspike 
      intervals (ISIs) decreased with age; (2) the occurrence of neurons with shorter 
      mean ISIs (less than 400 ms) increased with age; (3) the occurrence of neurons 
      with burst activity increased with age; (4) burst activity became more complex 
      with age; and (5) the rate of burst occurrence in neurons with burst activity 
      increased with age. Neurons within each region of the basal ganglia had 
      characteristic patterns of spontaneous activity. Furthermore, the developmental 
      patterns of spontaneous neuronal activity were different in each structure. The 
      spontaneous activity of GP-Ento and SN neurons matured before the spontaneous 
      activity of Cd neurons. Thus, spontaneous firing may mature in the output nuclei 
      of the basal ganglia prior to its maturation in the Cd.
FAU - Levine, M S
AU  - Levine MS
FAU - Fisher, R S
AU  - Fisher RS
FAU - Hull, C D
AU  - Hull CD
FAU - Buchwald, N A
AU  - Buchwald NA
LA  - eng
GR  - 1T32MH15345/MH/NIMH NIH HHS/United States
GR  - HD 04612/HD/NICHD NIH HHS/United States
GR  - HD 05958/HD/NICHD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Brain Res
JT  - Brain research
JID - 0045503
SB  - IM
MH  - Action Potentials
MH  - Age Factors
MH  - Animals
MH  - Cats
MH  - Caudate Nucleus/*growth & development
MH  - Globus Pallidus/*growth & development
MH  - Mesencephalon/*growth & development
MH  - Neural Inhibition
MH  - Substantia Nigra/*growth & development
MH  - Synaptic Transmission
EDAT- 1982/03/01 00:00
MHDA- 1982/03/01 00:01
CRDT- 1982/03/01 00:00
PHST- 1982/03/01 00:00 [pubmed]
PHST- 1982/03/01 00:01 [medline]
PHST- 1982/03/01 00:00 [entrez]
AID - 10.1016/0165-3806(82)90009-8 [doi]
PST - ppublish
SO  - Brain Res. 1982 Mar;255(3):429-41. doi: 10.1016/0165-3806(82)90009-8.