PMID- 6291047
OWN - NLM
STAT- MEDLINE
DCOM- 19821221
LR  - 20220311
IS  - 0027-8424 (Print)
IS  - 1091-6490 (Electronic)
IS  - 0027-8424 (Linking)
VI  - 79
IP  - 18
DP  - 1982 Sep
TI  - Detection and cloning of human DNA sequences related to the mouse mammary tumor 
      virus genome.
PG  - 5503-7
AB  - Sequences related to the mouse mammary tumor virus (MMTV) genome have been 
      detected in fragments of restricted human cellular DNA. These results were 
      obtained by using recombinant DNA containing the MMTV proviral genome and 
      lowering the stringency of blot-hybridization conditions. The MMTV genome also 
      reacts with unique families of fragments in restricted cellular DNA from other 
      mammalian species but not with salmon sperm DNA. A clone that reacted with 
      labeled MMTV proviral DNA was selected from a human DNA library in Charon 4A. 
      Under stringent conditions, a 3.7-kilobase MMTV-related EcoRI fragment of this 
      clone hybridized with many of the same EcoRI restriction fragments of human 
      cellular DNA detectable with MMTV proviral DNA under low-stringency conditions. 
      Specific fragments of the human clone were shown to contain sequences related to 
      the molecularly cloned gag, pol, and env regions of the MMTV genome.
FAU - Callahan, R
AU  - Callahan R
FAU - Drohan, W
AU  - Drohan W
FAU - Tronick, S
AU  - Tronick S
FAU - Schlom, J
AU  - Schlom J
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Proc Natl Acad Sci U S A
JT  - Proceedings of the National Academy of Sciences of the United States of America
JID - 7505876
RN  - 0 (DNA, Neoplasm)
RN  - 0 (DNA, Recombinant)
RN  - 0 (DNA, Viral)
RN  - 9007-49-2 (DNA)
RN  - EC 3.1.21.- (DNA Restriction Enzymes)
SB  - IM
MH  - Base Sequence
MH  - *Cloning, Molecular
MH  - DNA/*genetics/isolation & purification
MH  - DNA Restriction Enzymes
MH  - DNA, Neoplasm/*genetics/isolation & purification
MH  - DNA, Recombinant
MH  - DNA, Viral/*genetics
MH  - *Genes, Viral
MH  - Humans
MH  - Mammary Tumor Virus, Mouse/*genetics
MH  - Molecular Weight
MH  - Nucleic Acid Hybridization
PMC - PMC346932
EDAT- 1982/09/01 00:00
MHDA- 1982/09/01 00:01
PMCR- 1983/03/01
CRDT- 1982/09/01 00:00
PHST- 1982/09/01 00:00 [pubmed]
PHST- 1982/09/01 00:01 [medline]
PHST- 1982/09/01 00:00 [entrez]
PHST- 1983/03/01 00:00 [pmc-release]
AID - 10.1073/pnas.79.18.5503 [doi]
PST - ppublish
SO  - Proc Natl Acad Sci U S A. 1982 Sep;79(18):5503-7. doi: 10.1073/pnas.79.18.5503.