PMID- 629424
OWN - NLM
STAT- MEDLINE
DCOM- 19780426
LR  - 20170214
IS  - 0003-3197 (Print)
IS  - 0003-3197 (Linking)
VI  - 29
IP  - 1
DP  - 1978 Jan
TI  - Isovolumic relaxation time in normal subjects and patients with cardiac disease: 
      comparison of determinations made with echocardiographic techniques and apex 
      cardiography.
PG  - 7-15
AB  - Isovolumic relaxation time (IVRT) was determined in 17 controls and 41 patients. 
      Nine patients had ischemic heart disease (IHD), 7 mitral prolapse (MVPS), 13 
      hypertension (HPB), 7 pregnancy (P), and 5 cardiomyopathy (CM). Echocardiographic 
      measurements of IVRT were made from the aortic second sound to the rapid opening 
      of the mitral valve (A2D1). Determinations by apexcardiography were made from the 
      aortic second sound to the 0 point (A2O). The IVRT was distinctly shorter when 
      assessed by A2D1 than by conventional apexdardiography in conventional 
      apexcardiography in controls (69.2 +/- 16.4 msec vs 118.7 +/- 16.5 msec) and in 
      patients with cardiac disease. The IVRT in 9 older normal controls (mean age 47.7 
      years) was longer than in 8 younger ones (age 26.3 +/- 4.9 years). Patients with 
      myocardial disease (IHD, HBP, and CM) had prolonged IVRTs when compared to normal 
      subjects. Pregnant subjects had shortened intervals. IVRT may be a sensitive 
      indicator of disturbances in myocardial contractility and may be shortened and 
      enhanced contractility.
FAU - Araoye, M A
AU  - Araoye MA
FAU - Rubler, S
AU  - Rubler S
FAU - Holford, F D
AU  - Holford FD
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Angiology
JT  - Angiology
JID - 0203706
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - *Cardiac Volume
MH  - Coronary Disease/physiopathology
MH  - *Echocardiography
MH  - Female
MH  - Heart Diseases/*physiopathology
MH  - Heart Valve Diseases/physiopathology
MH  - Humans
MH  - Hypertension/physiopathology
MH  - *Kinetocardiography
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve
MH  - *Myocardial Contraction
MH  - Phonocardiography
MH  - Pregnancy
MH  - Prolapse
MH  - Time Factors
EDAT- 1978/01/01 00:00
MHDA- 1978/01/01 00:01
CRDT- 1978/01/01 00:00
PHST- 1978/01/01 00:00 [pubmed]
PHST- 1978/01/01 00:01 [medline]
PHST- 1978/01/01 00:00 [entrez]
AID - 10.1177/000331977802900102 [doi]
PST - ppublish
SO  - Angiology. 1978 Jan;29(1):7-15. doi: 10.1177/000331977802900102.