PMID- 6307426
OWN - NLM
STAT- MEDLINE
DCOM- 19830920
LR  - 20131121
IS  - 0365-9615 (Print)
IS  - 0365-9615 (Linking)
VI  - 96
IP  - 7
DP  - 1983 Jul
TI  - [Hormone-dependent enhancement of malignant phenotype in cells infected with 
      mouse mammary tumor virus (MMTV), and role of antigen transduction in this 
      process].
PG  - 87-9
AB  - Mouse mammary tumor virus (MMTV) is known to infect heterologous cells but it 
      does not appear that it alters their growth or morphological characteristics. 
      Djungarian hamster mammary tumor cells infected with MMTV were found to increase 
      the ability of the above cells to grow in semi-solid media. This effect was 
      demonstrable only in the presence of insulin and dexamethasone in cultural media. 
      Meanwhile non-infected cells were discovered to show no responsiveness to 
      hormones. The expression of non-viral antigen revealed by allogeneic anti-Thy 1.2 
      on the surface of infected cells was shown by the use of the cytotoxic test and 
      immunofluorescence technique. However, the use of monoclonal anti-Thy 1.2 
      antibodies failed to prove that antigen in question was structural virion protein 
      or Thy 1.2 antigen.
FAU - Litvinov, S V
AU  - Litvinov SV
FAU - Kriukova, I N
AU  - Kriukova IN
LA  - rus
PT  - English Abstract
PT  - Journal Article
TT  - Gormonozavisimoe povyshenie opukholevogo fenotipa kletok, zarazhennykh virusom 
      raka molochnoi zhelezy myshei (MMTV), i rol' v etom protsesse transdutsiruemykh 
      im antigenov.
PL  - Russia (Federation)
TA  - Biull Eksp Biol Med
JT  - Biulleten' eksperimental'noi biologii i meditsiny
JID - 0370627
RN  - 0 (Antigens)
RN  - 0 (Insulin)
RN  - 7S5I7G3JQL (Dexamethasone)
SB  - IM
MH  - Animals
MH  - Antigens/*genetics
MH  - Cell Line
MH  - Cell Transformation, Neoplastic
MH  - Cricetinae
MH  - Dexamethasone/*immunology
MH  - Insulin/*immunology
MH  - Mammary Neoplasms, Experimental/genetics
MH  - Mammary Tumor Virus, Mouse/*genetics
MH  - Mice
MH  - Phenotype
MH  - *Transduction, Genetic
EDAT- 1983/07/01 00:00
MHDA- 1983/07/01 00:01
CRDT- 1983/07/01 00:00
PHST- 1983/07/01 00:00 [pubmed]
PHST- 1983/07/01 00:01 [medline]
PHST- 1983/07/01 00:00 [entrez]
PST - ppublish
SO  - Biull Eksp Biol Med. 1983 Jul;96(7):87-9.