PMID- 6307613
OWN - NLM
STAT- MEDLINE
DCOM- 19830923
LR  - 20190515
IS  - 0149-5992 (Print)
IS  - 0149-5992 (Linking)
VI  - 6
IP  - 3
DP  - 1983 May-Jun
TI  - Serum lipids and lipoproteins in insulin-dependent diabetic subjects during 
      high-carbohydrate, high-fiber diet.
PG  - 224-30
AB  - The response of blood glucose and serum lipids and lipoproteins to a 
      high-carbohydrate, high-fiber, low-fat diet was assessed in 10 insulin-dependent 
      diabetic subjects. The diet contained approximately 60% of calories as 
      carbohydrate (CHO) and 20% as fat. The patients were followed for 2 wk in a 
      metabolic ward and subsequently for 4 wk at home without changing insulin dosage. 
      During this 6-wk period, the fasting blood glucose fell from 10.6 +/- 1.1 to 8.9 
      +/- 1.3 mmol/L (NS); HbA1 fell from 11.7 +/- 0.5 to 11.0 +/- 0.7% (P less than 
      0.05). Serum total triglyceride and very-low-density lipoprotein levels remained 
      unchanged. After 2 wk in the ward on a high-CHO diet, total cholesterol fell by 
      15% (P less than 0.01), LDL cholesterol by 16% (P less than 0.001), and HDL 
      cholesterol by 10% (P less than 0.05). The fall of HDL cholesterol was due to a 
      decrease of HDL3 cholesterol only. After the 4-wk home period on a high-CHO diet, 
      the observed lipoprotein changes were reversed. Heparin-releasable adipose tissue 
      LPL activity was not influenced by a high-CHO diet. In conclusion, a 
      high-carbohydrate, high-fiber, low-fat diet did not deteriorate the diabetic 
      control, and it had no unfavorable effects on serum lipids or lipoproteins.
FAU - Taskinen, M R
AU  - Taskinen MR
FAU - Nikkila, E A
AU  - Nikkila EA
FAU - Ollus, A
AU  - Ollus A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 0 (Dietary Fiber)
RN  - 0 (Insulin)
RN  - 0 (Lipids)
RN  - 0 (Lipoproteins)
RN  - 0 (Triglycerides)
RN  - 97C5T2UQ7J (Cholesterol)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Blood Glucose/analysis
MH  - Cholesterol/blood
MH  - Circadian Rhythm
MH  - Diabetes Mellitus/*blood/diet therapy
MH  - *Diet, Diabetic
MH  - Dietary Carbohydrates/administration & dosage
MH  - Dietary Fats/administration & dosage
MH  - Dietary Fiber/administration & dosage
MH  - Female
MH  - Humans
MH  - Insulin/deficiency
MH  - Lipids/*blood
MH  - Lipoproteins/blood
MH  - Male
MH  - Triglycerides/blood
EDAT- 1983/05/01 00:00
MHDA- 1983/05/01 00:01
CRDT- 1983/05/01 00:00
PHST- 1983/05/01 00:00 [pubmed]
PHST- 1983/05/01 00:01 [medline]
PHST- 1983/05/01 00:00 [entrez]
AID - 10.2337/diacare.6.3.224 [doi]
PST - ppublish
SO  - Diabetes Care. 1983 May-Jun;6(3):224-30. doi: 10.2337/diacare.6.3.224.