PMID- 6322878
OWN - NLM
STAT- MEDLINE
DCOM- 19840518
LR  - 20131121
IS  - 0365-9615 (Print)
IS  - 0365-9615 (Linking)
VI  - 97
IP  - 3
DP  - 1984 Mar
TI  - [Metabolic reaction of leukocytes in the course of experimental traumatic shock 
      of varying intensity and on exposure to obzidan].
PG  - 287-90
AB  - In stress-resistant animals exposed to 5-minute immobilization, the metabolic 
      reaction of leukocytes was marked by an increase in the activity of G-6-PDH, 
      hexokinase (HK), cytochrome oxidase (CCO) accompanied by a decrease in the 
      activity of succinate dehydrogenase (SDH). In stress-labile animals, there was a 
      decrease in the activity of G-6-PDH, HK, CCO with an increase in the activity of 
      SDH. The orientation of enzymatic processes in leukocytes of stress-labile 
      animals after immobilization and of stress-resistant animals following 
      intravenous injection of propranolol was discovered to be similar. After 
      propranolol injection leukocytes did not show any glucose, while the activity of 
      G-6-PDH, HK and CCO descended. Injection of propranolol decreased the animal's 
      resistance to traumatic shock. In stress-resistant animals exposed to trauma 
      after the blockade of beta-adrenoreactive structures, the metabolic reaction was 
      marked by low mobility restitution of energy processes as was the case in 
      stress-labile animals during the development of a severe shock.
FAU - Mikashinovich, Z I
AU  - Mikashinovich ZI
LA  - rus
PT  - English Abstract
PT  - Journal Article
TT  - Metabolicheskaia reaktsiia leikotsitov pri raznoi tiazhesti techeniia 
      eksperimental'nogo travmaticheskogo shoka i deistvii obzidana.
PL  - Russia (Federation)
TA  - Biull Eksp Biol Med
JT  - Biulleten' eksperimental'noi biologii i meditsiny
JID - 0370627
RN  - 0 (Blood Glucose)
RN  - 0 (Lactates)
RN  - 0 (Pyruvates)
RN  - 9Y8NXQ24VQ (Propranolol)
RN  - EC 1.1.1.49 (Glucosephosphate Dehydrogenase)
RN  - EC 1.3.99.1 (Succinate Dehydrogenase)
RN  - EC 1.9.3.1 (Electron Transport Complex IV)
RN  - EC 2.7.1.1 (Hexokinase)
SB  - IM
MH  - Adaptation, Physiological/drug effects
MH  - Animals
MH  - Blood Glucose/metabolism
MH  - Dogs
MH  - Electron Transport Complex IV/blood
MH  - Glucosephosphate Dehydrogenase/blood
MH  - Hexokinase/blood
MH  - Lactates/blood
MH  - Leukocyte Count
MH  - Leukocytes/*metabolism
MH  - Male
MH  - Propranolol/*pharmacology
MH  - Pyruvates/blood
MH  - Shock, Traumatic/*blood
MH  - Succinate Dehydrogenase/blood
EDAT- 1984/03/01 00:00
MHDA- 1984/03/01 00:01
CRDT- 1984/03/01 00:00
PHST- 1984/03/01 00:00 [pubmed]
PHST- 1984/03/01 00:01 [medline]
PHST- 1984/03/01 00:00 [entrez]
PST - ppublish
SO  - Biull Eksp Biol Med. 1984 Mar;97(3):287-90.