PMID- 6330304
OWN - NLM
STAT- MEDLINE
DCOM- 19840808
LR  - 20190630
IS  - 0022-3042 (Print)
IS  - 0022-3042 (Linking)
VI  - 43
IP  - 2
DP  - 1984 Aug
TI  - Beta-adrenergic binding sites in fetal rat brain.
PG  - 578-81
AB  - The ontogeny of beta-adrenergic binding sites was studied in forebrain 
      homogenates from male and female rats. Specific [3H]dihydroalprenolol binding was 
      defined by the difference between binding in the presence and in the absence of 
      330 nM (+)oxprenolol. Significant binding was detected at prenatal stages. The 
      dissociation constants (KD) of [3H]dihydroalprenolol binding were similar at 
      gestational day (GD) 19 3/4 and postnatal day (PN) 31. Binding was first detected 
      in forebrain at GD 15 3/4. The amount of binding sites increased until PN 31, 
      when adult values were reached. No sex differences could be detected at any of 
      the stages tested (GD 19 3/4-PN 31).
FAU - Bruinink, A
AU  - Bruinink A
FAU - Lichtensteiger, W
AU  - Lichtensteiger W
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Neurochem
JT  - Journal of neurochemistry
JID - 2985190R
RN  - 0 (Receptors, Adrenergic, beta)
RN  - 60106-89-0 (Dihydroalprenolol)
SB  - IM
MH  - Aging
MH  - Animals
MH  - Brain/*embryology/growth & development/metabolism
MH  - Dihydroalprenolol/metabolism
MH  - Female
MH  - Fetus
MH  - Gestational Age
MH  - Kinetics
MH  - Pregnancy
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Receptors, Adrenergic, beta/*metabolism
EDAT- 1984/08/01 00:00
MHDA- 1984/08/01 00:01
CRDT- 1984/08/01 00:00
PHST- 1984/08/01 00:00 [pubmed]
PHST- 1984/08/01 00:01 [medline]
PHST- 1984/08/01 00:00 [entrez]
AID - 10.1111/j.1471-4159.1984.tb00937.x [doi]
PST - ppublish
SO  - J Neurochem. 1984 Aug;43(2):578-81. doi: 10.1111/j.1471-4159.1984.tb00937.x.