PMID- 6360749
OWN - NLM
STAT- MEDLINE
DCOM- 19840224
LR  - 20170214
IS  - 0300-0605 (Print)
IS  - 0300-0605 (Linking)
VI  - 11
IP  - 6
DP  - 1983
TI  - Efficacy and safety of a non-acetylated salicylate, choline magnesium 
      trisalicylate, in the treatment of rheumatoid arthritis.
PG  - 343-8
AB  - The results of three double-blind, multicentre trials are reviewed to compare the 
      efficacy of acetysalicylic acid (ASA) and a non-acetylated salicylate, choline 
      magnesium trisalicylate (CMT), in the treatment of rheumatoid arthritis. In each 
      trial, patients were randomly assigned to receive comparable doses of salicylate 
      as either ASA or CMT. Mean values for clinical indicators of rheumatoid arthritis 
      (number of painful joints, articular index, number of swollen joints, swelling 
      index, duration of morning stiffness) showed similar or greater improvement among 
      groups of patients receiving CMT, compared to those receiving ASA. In addition, 
      the incidence of gastro-intestinal side-effects was lower among patients 
      receiving CMT.
FAU - Rothwell, K G
AU  - Rothwell KG
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - England
TA  - J Int Med Res
JT  - The Journal of international medical research
JID - 0346411
RN  - 0 (Anti-Inflammatory Agents)
RN  - 0 (Salicylates)
RN  - DJJ95FJP1H (choline magnesium trisalicylate)
RN  - N91BDP6H0X (Choline)
RN  - R16CO5Y76E (Aspirin)
SB  - IM
MH  - Anti-Inflammatory Agents/administration & dosage/*therapeutic use
MH  - Arthritis, Rheumatoid/*drug therapy
MH  - Aspirin/administration & dosage/therapeutic use
MH  - Choline/administration & dosage/adverse effects/*analogs & 
      derivatives/therapeutic use
MH  - Clinical Trials as Topic
MH  - Double-Blind Method
MH  - Humans
MH  - Random Allocation
MH  - Salicylates/administration & dosage/adverse effects/*therapeutic use
EDAT- 1983/01/01 00:00
MHDA- 1983/01/01 00:01
CRDT- 1983/01/01 00:00
PHST- 1983/01/01 00:00 [pubmed]
PHST- 1983/01/01 00:01 [medline]
PHST- 1983/01/01 00:00 [entrez]
AID - 10.1177/030006058301100604 [doi]
PST - ppublish
SO  - J Int Med Res. 1983;11(6):343-8. doi: 10.1177/030006058301100604.