PMID- 6361858
OWN - NLM
STAT- MEDLINE
DCOM- 19840224
LR  - 20061115
IS  - 0306-0632 (Print)
IS  - 0306-0632 (Linking)
VI  - 7
IP  - 3-4
DP  - 1983
TI  - The effect of feeding Streptococcus faecium upon Escherichia coli induced 
      diarrhea in gnotobiotic pigs.
PG  - 5-12
AB  - Streptococcus faecium (Sf) was fed to gnotobiotic pigs to control colibacillosis. 
      Three strains of Escherichia coli (Ec) were used. Strain 0:K103,987p:NM of Ec fed 
      to pigs without Sf developed severe diarrhea which persisted for several days. 
      Those pigs given Sf and Ec had less diarrhea, recovered earlier, and had better 
      weight gains than Ec only pigs. Two other strains of Ec (0157:K88ac:H19 and 
      08:K87,K88ab:H19) which were more virulent developed severe diarrhea and death in 
      5 of 8 pigs given Ec only. Those fed Sf and challenged with Ec developed some 
      diarrhea, but the pigs gained weight and none of the pigs died. Bacterial counts 
      of Ec and Sf from 3 different levels of small intestine and cecum were 
      comparable. The counts were reduced for both organisms in those pigs with dual 
      colonization. It would appear that feeding Sf reduced the toxic effect of Ec and 
      prevented a generalized infection and death. Forty-eight litters of 
      surgically-obtained colostrum-deprived specific-pathogen-free (SPF) pigs for 
      repopulating swine production units were started on Sf probiotic; 48 preceding 
      litters not fed Sf were used for comparison. Those fed Sf had a mortality rate of 
      8.5% as compared to 18% for those not fed Sf.
FAU - Underdahl, N R
AU  - Underdahl NR
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Prog Food Nutr Sci
JT  - Progress in food & nutrition science
JID - 7508713
SB  - IM
MH  - Animals
MH  - Diarrhea/*etiology
MH  - Escherichia coli/*pathogenicity
MH  - Germ-Free Life
MH  - Intestines/*microbiology
MH  - Streptococcus/*physiology
MH  - Swine
EDAT- 1983/01/01 00:00
MHDA- 1983/01/01 00:01
CRDT- 1983/01/01 00:00
PHST- 1983/01/01 00:00 [pubmed]
PHST- 1983/01/01 00:01 [medline]
PHST- 1983/01/01 00:00 [entrez]
PST - ppublish
SO  - Prog Food Nutr Sci. 1983;7(3-4):5-12.