PMID- 6370165
OWN - NLM
STAT- MEDLINE
DCOM- 19840523
LR  - 20131121
IS  - 0003-9926 (Print)
IS  - 0003-9926 (Linking)
VI  - 144
IP  - 5
DP  - 1984 May
TI  - Arrhythmia during insulin-induced hypoglycemia in a diabetic patient.
PG  - 1068-9
AB  - The temporal relationship between the level of blood glucose and the frequency of 
      ventricular premature contractions (VPCs) during 24 hours was examined in a 
      45-year-old man with diabetes mellitus who was treated with a regular insulin 
      injection. The number of VPCs increased sharply when the blood glucose level fell 
      to about 50 mg/dL while the patient was awake. There was a minimal increase in 
      VPCs during sleep, despite a decrease to 21 mg/dL in the blood glucose level. The 
      insulin tolerance test produced frequent VPCs during hypoglycemia, which was 
      suppressed by glucose administration. Changes in the level of plasma epinephrine 
      correlated well with changes in the frequency of VPCs. These data suggest that 
      increased levels of plasma epinephrine may have played a role in the genesis of 
      VPCs that occurred during insulin-induced hypoglycemia.
FAU - Shimada, R
AU  - Shimada R
FAU - Nakashima, T
AU  - Nakashima T
FAU - Nunoi, K
AU  - Nunoi K
FAU - Kohno, Y
AU  - Kohno Y
FAU - Takeshita, A
AU  - Takeshita A
FAU - Omae, T
AU  - Omae T
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Arch Intern Med
JT  - Archives of internal medicine
JID - 0372440
RN  - 0 (Blood Glucose)
RN  - 0 (Insulin)
RN  - RWP5GA015D (Potassium)
SB  - IM
MH  - Arrhythmias, Cardiac/blood/*chemically induced
MH  - Blood Glucose/analysis
MH  - Circadian Rhythm
MH  - Diabetes Mellitus/blood/*drug therapy
MH  - Heart Ventricles/physiopathology
MH  - Humans
MH  - Hypoglycemia/blood/*chemically induced
MH  - Insulin/adverse effects/therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Potassium/blood
EDAT- 1984/05/01 00:00
MHDA- 1984/05/01 00:01
CRDT- 1984/05/01 00:00
PHST- 1984/05/01 00:00 [pubmed]
PHST- 1984/05/01 00:01 [medline]
PHST- 1984/05/01 00:00 [entrez]
PST - ppublish
SO  - Arch Intern Med. 1984 May;144(5):1068-9.