PMID- 6421288
OWN - NLM
STAT- MEDLINE
DCOM- 19840305
LR  - 20190612
IS  - 0006-291X (Print)
IS  - 0006-291X (Linking)
VI  - 117
IP  - 3
DP  - 1983 Dec 28
TI  - Antibodies to a synthetic peptide corresponding to the N-terminal end of mouse 
      gamma interferon (IFN gamma).
PG  - 866-71
AB  - Antibodies to an N-terminal synthetic peptide of mouse gamma interferon (MoIFN 
      gamma) neutralized the antiviral activity of MoIFN gamma but not MoIFN 
      alpha/beta, human IFN alpha (HuIFN alpha), HuIFN beta or cynomologus monkey IFN 
      gamma (CynIFN gamma). Comparatively, antibodies to mouse N-terminal synthetic 
      peptide showed only 10% reciprocal cross-reactivity in neutralization tests 
      against heterologous HuIFN gamma and 13% cross-reactivity in the ELISA test 
      against Hu N-terminal peptide. The predetermined specificity of these antibodies 
      make them powerful tools for studying antigenic relatedness and biological 
      properties of IFN gamma s.
FAU - Langford, M P
AU  - Langford MP
FAU - Gray, P W
AU  - Gray PW
FAU - Stanton, G J
AU  - Stanton GJ
FAU - Lakhchaura, B
AU  - Lakhchaura B
FAU - Chan, T S
AU  - Chan TS
FAU - Johnson, H M
AU  - Johnson HM
LA  - eng
GR  - CA27590/CA/NCI NIH HHS/United States
GR  - CA35968/CA/NCI NIH HHS/United States
GR  - EY01715/EY/NEI NIH HHS/United States
GR  - etc.
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Biochem Biophys Res Commun
JT  - Biochemical and biophysical research communications
JID - 0372516
RN  - 0 (Antibodies)
RN  - 0 (Peptide Fragments)
RN  - 82115-62-6 (Interferon-gamma)
SB  - IM
MH  - Animals
MH  - Antibodies/*isolation & purification
MH  - Antibody Specificity
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Humans
MH  - Interferon-gamma/*immunology
MH  - Mice
MH  - Neutralization Tests
MH  - Peptide Fragments/*immunology
MH  - Rabbits
EDAT- 1983/12/28 00:00
MHDA- 1983/12/28 00:01
CRDT- 1983/12/28 00:00
PHST- 1983/12/28 00:00 [pubmed]
PHST- 1983/12/28 00:01 [medline]
PHST- 1983/12/28 00:00 [entrez]
AID - 0006-291X(83)91676-5 [pii]
AID - 10.1016/0006-291x(83)91676-5 [doi]
PST - ppublish
SO  - Biochem Biophys Res Commun. 1983 Dec 28;117(3):866-71. doi: 
      10.1016/0006-291x(83)91676-5.