PMID- 6425154
OWN - NLM
STAT- MEDLINE
DCOM- 19840621
LR  - 20031114
IS  - 0015-5683 (Print)
IS  - 0015-5683 (Linking)
VI  - 31
IP  - 1
DP  - 1984
TI  - Experimental infection of sheep with Bhanja virus.
PG  - 79-84
AB  - Seven juvenile sheep were infected subcutaneously (s.c.) or intracerebrally 
      (i.c.) with Bhanja virus. Distinct symptoms of CNS affection (ataxia, pareses) 
      were observed only in the case of i.c. application of a massive dose (10(-7) to 
      10(9) SMicLD50) of the Bg 336/336 strain. A short-term and low viremia (one to 
      four days p.i.) was ascertained after i.c. infection with a dose of 10(4.7) to 
      10(9.2) SMicLD50 of the same strain. On the other hand, the high titres of 
      neutralization antibodies were detected even after inoculation of small doses of 
      the virus (e.g. 50 SMicLD50). Unlike the symptomatic response, the immune 
      response of sheep to Bhanja virus is high.
FAU - Madr, V
AU  - Madr V
FAU - Hubalek, Z
AU  - Hubalek Z
FAU - Zendulkova, D
AU  - Zendulkova D
LA  - eng
PT  - Journal Article
PL  - Czech Republic
TA  - Folia Parasitol (Praha)
JT  - Folia parasitologica
JID - 0065750
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - Animals
MH  - Antibodies, Viral/biosynthesis
MH  - Ataxia/veterinary
MH  - Bunyaviridae/immunology
MH  - Bunyaviridae Infections/immunology/microbiology/physiopathology/*veterinary
MH  - Disease Susceptibility
MH  - Female
MH  - Male
MH  - Paresis/veterinary
MH  - Sheep
MH  - Sheep Diseases/immunology/*microbiology
MH  - Viremia/veterinary
EDAT- 1984/01/01 00:00
MHDA- 1984/01/01 00:01
CRDT- 1984/01/01 00:00
PHST- 1984/01/01 00:00 [pubmed]
PHST- 1984/01/01 00:01 [medline]
PHST- 1984/01/01 00:00 [entrez]
PST - ppublish
SO  - Folia Parasitol (Praha). 1984;31(1):79-84.